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CompletedNCT05388955Updated Dec 11, 2023

Risk Assessment Tool for Graft Survival in Pediatric Kidney Transplantation

An observational study in Kidney Transplant Failure and Rejection and Pediatric Kidney Disease, sponsored by Radboud University Medical Center. Completed. Open to participants aged 0 Years to 18 Years. Per ClinicalTrials.gov, last updated 2023-12-11.

Sponsored by Radboud University Medical Center · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
1,425
Ages
0 Years to 18 Years
Sex
All
01

Study summary

Registry study in which data of all pediatric kidney recipients in the Netherlands (registered in the Nederlandse Orgaan Transplantatie Registry) are studied to develop a risk calculator for graft loss.

Read the detailed description

The pre-transplantation parameters of all recipients are used to do a multivariable regression analysis.

The B-coefficients of this analysis will be used to develop a risk calculator that predicts graft survival after transplantation per year of transplantation.

02

Conditions studied

  • Kidney Transplant Failure and Rejection
  • Pediatric Kidney Disease

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03

In context

Kidney Diseases

3,840 studies on the registry are indexed under Kidney Diseases; 500 are open to participants now.

This study's enrollment of 1,425 is above the median of 192 across 1,033 observational studies indexed under Kidney Diseases.

Browse Kidney Diseases studies →

Lead sponsor

Radboud University Medical Center is the lead sponsor of 959 studies on the registry; 134 are open to participants now.

Of its 6 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
0 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All pediatric kidney recipients that received their kidney \<18 years in the Netherlands

Inclusion criteria

Pediatric kidney recipients

  • transplantation in the Netherlands
  • signed informed consent

Exclusion criteria

Exclusion Criteria:

  • combined transplantation (pancreas-kidney of liver-kidney transplantation)
  • No informed consent
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
1,425 participants (actual)
Patient registry
No

Interventions

  • OtherNone, transplantation recipients

    None, observational

06

What researchers measure

Primary outcomes

  1. Graft survival

    Functioning graft of death with functioning graft. Survival graph: Percentage recipients with a functioning graft over time

    Time frame: Up to 50 years after transplantation

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No — Not owner of the data, NOTR owns the data

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 11, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05388955
Lead sponsor
Radboud University Medical Center
Responsible party
Sponsor
First posted
May 24, 2022
Start date
Jan 1966
Primary completion
Jan 1, 2022
Completion
Jan 1, 2022
Last update
Dec 11, 2023

Study contacts

Liesbeth De Wall
principal investigator · Radboud University Medical Center

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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