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RecruitingNCT05388682Updated Sep 22, 2026

Treatment of Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement

An observational study in Takayasu Arteritis With Pulmonary Artery Involvement, Percutaneous Transluminal Pulmonary Angioplasty and PAH Targeted Medication, sponsored by Chinese Pulmonary Vascular Disease Research Group. Recruiting at 1 site in China. Per ClinicalTrials.gov, last updated 2026-09-22.

Sponsored by Chinese Pulmonary Vascular Disease Research Group · Observational

From the registry’s dates

  • Started Jan 2014; still recruiting 12 years 8 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Sex
All
01

Study summary

  1. Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement
  2. evaluate the efficacy of FAPI in predicting the activity and treatment efficacy of takayasu arteritis with pulmonary artery involvement
Read the detailed description

At baseline, FAPI and FDG are performed to evaluate the activity of takayasu arteritis with pulmonary artery involvement. FAPI is also used to predict the treatment efficacy and prognosis of takayasu arteritis with pulmonary artery involvement.

02

Conditions studied

  • Takayasu Arteritis With Pulmonary Artery Involvement
  • Percutaneous Transluminal Pulmonary Angioplasty
  • PAH Targeted Medication

Keywords

  • Percutaneous transluminal pulmonary angioplasty, Takayasu Arteritis with Pulmonary Artery Involvement
03

In context

Lead sponsor

Chinese Pulmonary Vascular Disease Research Group is the lead sponsor of 16 studies on the registry; 10 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients diagnosed with Takayasu arteries with pulmonary arteries involvement received either medical or percutaneous transluminal pulmonary angioplasty

Inclusion criteria

  • patients diagnosed with Takayasu arteries with pulmonary arteries involvement

Exclusion criteria

Exclusion Criteria:

  • Patients had pulmonary artery stenosis arising from CTEPH, fibrosing mediastinitis and congenital pulmonary artery stenosis
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (estimated)
Patient registry
No

Interventions

  • DevicePercutaneous transluminal pulmonary angioplasty

    Percutaneous transluminal pulmonary angioplasty

06

What researchers measure

Primary outcomes

  1. all cause death

    all cause death

    Time frame: 2014/1/1-2042/12/31

  2. mean pulmonary arterial pressure change

    change of mean pulmonary arterial pressure after treatment

    Time frame: 2014/1/1-2042/12/31

  3. pulmonary vascular resistance change

    chagne of pulmonary vascular resistance after treatment

    Time frame: 2014/1/1-2042/12/31

  4. 6MWD change

    change of six minute walk distance after treatment

    Time frame: 2014/1/1-2042/12/31

  5. peak VO2 change

    change of peak oxygen consumption after treatment

    Time frame: 2014/1/1-2042/12/31

  6. NT-proBNP change

    change of NT-proBNP after treatment

    Time frame: 2014/1/1-2042/12/31

  7. RV/LV change

    change of right ventricular end-diastolic diameter versus laboratory left ventricular end-diastolic diameterafter treatment

    Time frame: 2014/1/1-2042/12/31

  8. CI change

    change of cardiac index after treatment

    Time frame: 2014/1/1-2042/12/31

07

Study locations

1 of 1 sites recruiting
  • Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
    Beijing, China 100000, China
    • Zhihong Liu, doctor · Contact · 13269276067
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05388682
Lead sponsor
Chinese Pulmonary Vascular Disease Research Group
Responsible party
Sponsor
First posted
May 24, 2022
Start date
Jan 19, 2014
Primary completion
Dec 31, 2042 (estimated)
Completion
Dec 31, 2042 (estimated)
Last update
Sep 22, 2026

Study contacts

Zhihong Liu, doctor
Contact
zhihongliufuwai@163.com
86-010-88396589
zhihong Liu, doctor
principal investigator · Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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