An interventional study of salpingectomy and hysterectomy in Salpingectomy, Hysterectomy and Primary Ciliary Dyskinesia, sponsored by Centre Hospitalier Intercommunal Creteil. Terminated at 1 site in France. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-12.
Sponsored by Centre Hospitalier Intercommunal Creteil · Not applicable, Interventional, and Other
Primary Ciliary Dyskinesia associated with abnormalities of lateralization of organs (with existence of a situs inversus in 50% of cases) and secondary fertility disorders related in humans to abnormalities of mobility of sperm but very little data on the structure and function of tubal cilia in women
Primary Ciliary Dyskinesia (DCP) is a rare genetic disease (1 in 15,000 individuals at birth), which manifests itself in chronic respiratory infections (bronchopneumopathies and rhinosinusitis type) associated with abnormalities of lateralization of organs (with existence of a situs inversus in 50% of cases) and secondary fertility disorders related in humans to abnormalities of sperm mobility. However, there is very little data in the literature on the structure and function of tubal cilia in women with DCP.
Before considering a study of tubal cilia in patients with DCP, it seems necessary to specify in DCP patients or not DCP, the molecular and morphological composition of tubal cilia and to look for ciliary abnormalities in case of GEU
79 studies on the registry are indexed under Ciliary Motility Disorders; 26 are open to participants now.
This study's enrollment of 61 is above the median of 32 across 24 interventional studies indexed under Ciliary Motility Disorders.
Browse Ciliary Motility Disorders studies →Centre Hospitalier Intercommunal Creteil is the lead sponsor of 131 studies on the registry; 36 are open to participants now.
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Exclusion Criteria:
patients with salpingectomy for Ectopic Pregnancy
Procedure: salpingectomy
patients with hysterectomy for prolapsus, adenomyosis or myomectomy
Procedure: hysterectomy
Removal of one of the fallopian tubes.
remove the uterus, whole or only part. It may also involve the removal of the cervix, ovaries, fallopian tubes and other surrounding structures.
morphological of tubal cilia
Molecular compositor of tubal ciliar by immunofluorescence study of 14 proteins in vivo and in vitro (tissue cells from patient fallopian tubes)
Time frame: through study completion, an average of 6 week after surgery
Molecular difference in tubal cilia between patients with or without GEU salpingectomy
compares molecular compositor of tubal ciliar by immunofluorecence study of 14 proteins in vivo and in vitro between patients with or without GEU salpingectomy
Time frame: through study completion, an average of 6 week after surgery
molecular tubal cilia
Ultrastructure morphology of tubal cell cilia by electron microscopy
Time frame: through study completion, an average of 6 week after surgery
functional composition of tubal cell by video microscopy
amplitude of moment by video microscopy
Time frame: through study completion, an average of 6 week after surgery
functional composition of tubal cell by video microscopy
frequency of moment by video microscopy
Time frame: through study completion, an average of 6 week after surgery
Ran from Nov 2022 to primary completion in Oct 2023, 10 months.
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This study is terminated, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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