An observational study in Aortic Aneurysm, Abdominal and Popliteal Artery Aneurysm, sponsored by Centre Hospitalier Universitaire Vaudois. Active, not recruiting at 5 sites in 2 countries. Open to participants aged 55 Years to 85 Years. Per ClinicalTrials.gov, last updated 2026-03-16.
Sponsored by Centre Hospitalier Universitaire Vaudois · Observational
Observational, prospective, cohort study to evaluate, by an opportunistic screening program based on vascular ultrasound, the prevalence and characteristics of Abdominal Aortic Aneurysm (AAA) and Popliteal Artery Aneurysm (PAA) in a female population as well as the prevalence and characteristics of PAA in male population.
Abdominal aortic aneurysm (AAA) remains a highly topical issue given the potentially dramatic consequences associated with its rupture. In men, the prevalence of AAA is declining, probably due to improved management of risk factors. However, the most recent studies and international recommendations have reaffirmed that screening for AAA in men is still important and cost-effective. In contrast, data regarding the risk and characteristics of AAA in women are very limited and outdated. For this reason, the recommendations are contrasting and not univocal. About 35% of patients with AAA have a second aneurysm more distally. Popliteal artery aneurysm (PAA) is the most common. Like AAA, PAA is often asymptomatic and its main complication is thrombotic occlusion resulting in acute/chronic ischemia of the affected limb and a high prevalence of permanent sequelae (mainly amputation). Data on epidemiology and risk factors of PAA are very limited in men and absent in women. In addition, the benefit of PAA screening has never been assessed so far.
The aim of this study is to evaluate, by an opportunistic screening program based on vascular ultrasound, the prevalence and characteristics of AAA and PAA in a female population as well as the prevalence and characteristics of PAA in male population. The project represents the first screening program for popliteal aneurysm. Finally, the results will allow us to better assess need for and modalities of a screening program.
473 studies on the registry are indexed under Aortic Aneurysm, Abdominal; 100 are open to participants now.
This study's enrollment of 507 is above the median of 166 across 220 observational studies indexed under Aortic Aneurysm, Abdominal.
Browse Aortic Aneurysm, Abdominal studies →Centre Hospitalier Universitaire Vaudois is the lead sponsor of 203 studies on the registry; 47 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Women or Men at high risk for aneurysmal disease
Exclusion Criteria:
Abdominal aortic measurement
Ultrasound of infrarenal aorta with diameter measured in mm
Time frame: 1 day
Popliteal artery measurement
Ultrasound of popliteal artery with diameter measured in mm
Time frame: 1 day
Smoking habits
Defined by active smoking, former smoking, never smoking
Time frame: 1 day
Other cardiovascular risk factors
Arterial hypertension, Diabetes, Dyslipidemia, Obesity
Time frame: 1 day
History of cardiovascular diseases
Coronary artery disease, cerebrovascular disease, lower extremity peripheral artery disease, venous thromboembolism
Time frame: 1 day
Family history for aneurysmal disease
First-degree relatives with aneurysmal disease
Time frame: 1 day
Time-consuming
Time needed to perform screening
Time frame: 1 day
Surgical intervention for aneurysm
Number of aneurysm operated during follow-up
Time frame: 36 months
This study is active, not recruiting, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire Vaudois