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CompletedNCT05306262CATALHYPNOANIUpdated Apr 8, 2026

Interest of Catalepsy in the Hypnotic Trance

An interventional study of Hypnosis session and Catalepsy in Hypnosis, sponsored by CMC Ambroise Paré. Completed at 1 site in France. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-08.

Sponsored by CMC Ambroise Paré · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
18 Years to 75 Years
Sex
All
01

Study summary

Catalepsy seems to facilitate hypnotic induction and deepen hypnotic trance, although no work confirms the usefulness of this technique which is in common use in hypnosis. Furthermore, it has been shown that the hypnotic trance state is accompanied by an increase in parasympathetic tone, the non-invasive measurement of which is easy by the ANI monitor (Analgesia Nociception Index).

The research hypothesis is that, by adding a body dissociation, catalepsy could facilitate and intensify the hypnotic trance, the intensity of which can be monitored and is proportional to the parasympathetic tone.

Read the detailed description

After randomization, subjects will either benefit from the normal hypnotic trance, or from the hypnotic trance associated with catalepsy of the hand.

T0 = installation in a sitting position and collection of an accompanying theme T1 = induction of the hypnotic trance (closing eyes) with restitution of the theme to the patient and suggestion of comfort over a period of 5 to 10 min T2 = validation of comfort by a pre-established signal T3 = return to consciousness (opening eyes) T4 = end of questionnaire about absorption, dissociation and time perception

02

Conditions studied

  • Hypnosis

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Keywords

  • Hypnosis
  • Catalepsy
  • Parasympathetic tone
  • Absorption
  • Dissociation
  • Perception of time
03

In context

Dissociative Disorders

41 studies on the registry are indexed under Dissociative Disorders; 13 are open to participants now.

This study's enrollment of 90 is above the median of 50 across 34 interventional studies indexed under Dissociative Disorders.

Browse Dissociative Disorders studies →

Lead sponsor

CMC Ambroise Paré is the lead sponsor of 47 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Healthy Volunteers
  • Consent for participation
  • Affiliation to the social security system

Exclusion criteria

Exclusion Criteria:

  • Arrhythmia (atrial fibrillation, pacemaker, defibrillator)
  • Autonomic nervous system disorder (paraplegia, epilepsy, etc.)
  • Pregnant or breastfeeding woman
  • Patients under protection of the adults (guardianship, curators or safeguard of justice)
  • Communication difficulties
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
90 participants (actual)

Study arms

  • Active comparator
    hypnotic trance

    Hypnosis session of comfort for 20 minutes

    Procedure: Hypnosis session

  • Experimental
    hypnotic trance + catalepsy

    Catalepsy + Hypnosis session of comfort for 20 minutes

    Procedure: Hypnosis session · Other: Catalepsy

Interventions

  • ProcedureHypnosis session

    Comfort hypnosis: accompaniment of a pleasant memory.

  • OtherCatalepsy

    Catalepsy of the hand.

06

What researchers measure

Primary outcomes

  1. Parasympathetic tone

    Analgesia Nociception Index (ANI)

    Time frame: 30 minutes

Secondary outcomes

  1. Absorption

    Numeric scale from 0 to 10 (0=not at all, 10=completely)

    Time frame: 30 minutes

  2. Dissociation

    Numeric scale from 0 to 10 (0=completely in the reality, 10=completely disconnected from reality)

    Time frame: 30 minutes

  3. Time perception (minute)

    Difference between the time of hypnosis session estimated by the patient and the actual time of hypnosis session (from closing to opening the eyes).

    Time frame: 30 minutes

  4. Variation of Heart Rate (beat per minute)

    Heart rate measured by a pulse oximeter

    Time frame: 30 minutes

  5. Variation of Respiratory Rate (breath per minute)

    Respiratory rate assessed by the investigator

    Time frame: 30 minutes

07

Study locations

1 site
  • Institut Emergences
    Rennes, France
08

References and documents

Publications

  • Boselli E, Radoykov S, Paqueron X, Virot C. Effects of hand catalepsy on subjective trance perception and relative parasympathetic tone in healthy volunteers during pleasant hypnotic session: a randomized controlled study. J Clin Monit Comput. 2024 Dec;38(6):1291-1296. doi: 10.1007/s10877-024-01178-7. Epub 2024 May 29. PubMed 38811463 ↗
09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from May 2022 to primary completion in May 2022, 0 months.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 23, 2022
First posted
Apr 1, 2022
StartActual
May 26, 2022
Primary completionActual
May 28, 2022
CompletionActual
May 28, 2022
Last update
Apr 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05306262
Lead sponsor
CMC Ambroise Paré
Responsible party
Sponsor
First posted
Apr 1, 2022
Start date
May 26, 2022
Primary completion
May 28, 2022
Completion
May 28, 2022
Last update
Apr 8, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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