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Status unknownNCT05270629Updated Mar 8, 2022

Supermicrosurgical Lymphvenous Bypass Intervention for Treatment

An observational study in Lymphedema of Leg, sponsored by Chang Gung Memorial Hospital. Status unknown at 1 site in Taiwan. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2022-03-08.

Sponsored by Chang Gung Memorial Hospital · Observational

The sponsor has not verified this record recently (last verified Feb 2022), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
87
Ages
18 Years to 100 Years
Sex
All
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Study summary

Background: In addition to antegrade anastomosis, retrograde anastomosis has been thought to offer further improvements after lymphaticovenous anastomosis (LVA) by bypassing the retrograde lymphatic flow. However, this concept has yet to be validated. The aim of this study was to determine the impacts on outcomes of performing both retrograde and antegrade anastomosis, as compared to antegrade-only anastomosis for treating lower limb lymphedema.

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Conditions studied

  • Lymphedema of Leg

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03

In context

Lymphedema

560 studies on the registry are indexed under Lymphedema; 135 are open to participants now.

This study's planned enrollment of 87 is below the median of 106 across 144 observational studies indexed under Lymphedema.

Browse Lymphedema studies →

Lead sponsor

Chang Gung Memorial Hospital is the lead sponsor of 1,064 studies on the registry; 235 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients (age > 18 years) with lower limb lymphedema patients were enrolled from March 2016 to December 2020.

Inclusion criteria

  • Lower limb lymphedema patients.

Exclusion criteria

Exclusion Criteria:

  • Patients who have had previous LVA, liposuction, or excisional therapy such as the Charles procedure were excluded.
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Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
87 participants (estimated)
Patient registry
No

Groups and cohorts

  • Lower limb lymphedema patients

    This was a retrospective cohort propensity score-matched study. Patients with lower limb lymphedema were enrolled.

    Other: Antegrade and retrograde anastomoses · Other: Antegrade-only anastomoses

Interventions

  • OtherAntegrade and retrograde anastomoses

    Patients who had received both antegrade and retrograde anastomoses.

  • OtherAntegrade-only anastomoses

    Patients who had received antegrade-only anastomoses.

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What researchers measure

Primary outcomes

  1. Magnetic resonance volumetry

    Magnetic resonance volumetry was used for outcome assessments. The primary endpoint was the volume change at 6 months after LVA.

    Time frame: 6 months after LVA

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Study locations

1 of 1 sites recruiting
  • Kaohsiung Chang Gung Memorial Hospital
    Kaohsiung, 83301, Taiwan
    Recruiting
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 8, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05270629
Lead sponsor
Chang Gung Memorial Hospital
Responsible party
Sponsor
First posted
Mar 8, 2022
Start date
Sep 6, 2021
Primary completion
Aug 31, 2022 (estimated)
Completion
Sep 5, 2022 (estimated)
Last update
Mar 8, 2022

Study contacts

Ching-Hua Hsieh, PhD
Contact
m93chinghua@gmail.com
+886-7-7317123 ext. 2947

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2022. You cannot join it, but the record below documents what was studied.

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