An observational study in Pertussis/Whooping Cough and Influenza Viral Infections, sponsored by Central Hospital, Nancy, France. Completed at 1 site in France. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-02-08.
Sponsored by Central Hospital, Nancy, France · Observational
Pertussis is a bacterial respiratory infection caused by Bordetella pertussis. Highly contagious, it is potentially serious and even fatal in infants under 6 months of age. The immunity acquired through vaccination is very limited in time, requiring regular booster shots. There is a passive protection of the newborn by the maternal-fetal transmission of maternal antibodies, but it is brief. The infant's first vaccination is given at 2 months of age and immunity is not acquired until the second injection at 4 months of age. The booster at 11 months of age is essential to prolong this immunity.
In order to protect infants under 6 months of age, France has recommended since 2004 the cocooning strategy, which consists of vaccinating people likely to be in close contact with the infant during this period. This vaccination is therefore proposed to adults who are planning to have children, to the entourage of pregnant women, and in the immediate post-partum period for the mother (and people who were not vaccinated during pregnancy). This strategy was put in place following the international recommendation of a forum of scientific experts, the Global Pertussis Initiative.
In France, vaccination against pertussis is not currently recommended during pregnancy. There is no contraindication to vaccination during pregnancy and it is recommended in many countries.
Influenza is a viral respiratory infection caused by Myxovirus influenzae, which is highly contagious.
In France, vaccination against influenza is recommended for pregnant women, regardless of the trimester of pregnancy. It is also recommended for the entourage of infants under 6 months of age with risk factors for severe influenza.
There are few recent data in the scientific literature regarding influenza and pertussis vaccination coverage among pregnant or postpartum women in France. In addition, the COVID19 pandemic has recently reopened the debate on vaccination of the general population and caregivers. Knowing the current status of vaccination coverage among pregnant women and caregivers, their knowledge and fears regarding vaccination could help improve the information provided by healthcare staff.
2,215 studies on the registry are indexed under Influenza, Human; 164 are open to participants now.
This study's enrollment of 254 is below the median of 300 across 305 observational studies indexed under Influenza, Human.
Browse Influenza, Human studies →Central Hospital, Nancy, France is the lead sponsor of 778 studies on the registry; 183 are open to participants now.
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Women over 18 years old, delivery after 35GA and healthcare staff of the University Maternity Hospital of Nancy in 2022. Person having received complete information about the research and not opposed to the study.
Exclusion Criteria:
women in immediate post partum
Other: Survey
health care personnel
Other: Survey
Collection of immunization status by questionnaire
Prevalence of influenza vaccination
To determine the rate of influenza immunization in immediate postpartum women and caregivers at the Nancy University Maternity Hospital in 2022 .
Time frame: 4 months
Prevalence of pertussis vaccination
To determine the rate of pertussis immunization in immediate postpartum and caregivers at the Nancy University Maternity Hospital in 2022
Time frame: 4 months
awareness of own vaccination status
To determine the awareness of own vaccination status (yes; no; unknown) in immediate postpartum women regarding their influenza and pertussis immunization
Time frame: 4 months
Knowledge about vaccination
To determine the rate of right answers to a questionnaire about knowledge of influenza and pertussis vaccination, and the possibility of vaccination during pregnancy.
Time frame: 4 months
opinion on vaccination during pregnancy
To determine the rate of differences in vaccination coverage and knowledge among postpartum women and healthcare staff.
Time frame: 4 months
readiness to receive pertussis and influenzae immunization
to answer the readiness (yes; no; already vaccinated) to receive immunization after answering the questionnaire
Time frame: 4 months
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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Central Hospital, Nancy, France