An observational study in COVID-19 and IVF, sponsored by Al Baraka Fertility Hospital. Completed at 1 site in Egypt. Open to female participants aged 20 Years to 38 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-01-20.
Sponsored by Al Baraka Fertility Hospital · Observational
Whilst the global COVID-19 pandemic is still evolving and there are many unknowns about the long-term effects of the virus on fertility and pregnancy, we found ourselves in need to offer some evidence-based guidance, that's why we decided to go for this study, to evaluate the relation of the covid-19 and the outcome of IVF/ICSI cycles. we found that there is no clear evidence that the previous exposure to Covid-19 virus infection can affect the outcome of ICSI cycles significantly.
This is an observational study, for 122 ICSI cycles conducted in Al- Baraka Fertility Hospital, Manama, Bahrain, and Al-Manea hospital, KSA between August 2020 and May 2021, and it was approved by the ethical committees. We compared the outcome results of those patients who got recovered from previous exposure to covid-19 (study group) with results of non-infected comparable patients (control group) After comparison of the basal characteristics in both groups, and we got assured that there is no significant difference regarding the demographic criteria between both groups, we found that there is no significant difference regarding the duration of stimulation, the total dose of stimulation, number of oocytes retrieved, number of metaphase 2 oocytes (MII), number of grade1-2 embryos, number of transferred embryos, day of embryo transfer and fertilization rate.
Although the fertilization rate was higher in Covid-19 free patients (52% vs. 50.6%), however, this difference is not statistically significant.
In the same way, the pregnancy rate was also higher in the covid-19 negative group (45.1% vs. 36.4%); however this difference was not statistically significant.
7,990 studies on the registry are indexed under COVID-19; 466 are open to participants now.
This study's enrollment of 122 is below the median of 268 across 3,208 observational studies indexed under COVID-19.
Browse COVID-19 studies →Al Baraka Fertility Hospital is the lead sponsor of 8 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
All women underwent individualized antagonist protocol
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
(previous covid-19 positive) n. =88
Other: covid-19
(covid-19 negative) n.=91
viral infection
number of mature oocytes (MII)
how many mature oocytes
Time frame: 10 days
total number of blastocysts
number of blastocysts
Time frame: 15 days
B-hcg
the clinical pregnancy rate.
Time frame: 4 weeks
Plan to share: Undecided
No publications or documents are linked to this record.
Ran from Aug 2020 to primary completion in May 2021, 9 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jan 2022. You cannot join it, but the record below documents what was studied.
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Al Baraka Fertility Hospital