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CompletedNCT05182814Updated Jun 13, 2022

Efficacy Testing of Collagen Drink on Skin Beauty and Sleep Aid

An interventional study of Placebo drink and Collagen Juice Drink in Skin Condition and Sleep Disturbance, sponsored by TCI Co., Ltd.. Completed at 1 site in Taiwan. Open to participants aged 20 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-06-13.

Sponsored by TCI Co., Ltd. · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
20 Years and older
Sex
All
01

Study summary

To assess Collagen Drink on skin condition and sleep quality improvement

02

Conditions studied

  • Skin Condition
  • Sleep Disturbance
03

In context

Dyssomnias

324 studies on the registry are indexed under Dyssomnias; 51 are open to participants now.

This study's enrollment of 60 is close to the median of 60 across 251 interventional studies indexed under Dyssomnias.

Browse Dyssomnias studies →

Lead sponsor

TCI Co., Ltd. is the lead sponsor of 60 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy adults aged above 20 years old

Exclusion criteria

Exclusion Criteria:

  • Subject who is not willing to participate in this study.
  • Patients with diseases of the skin, liver, kidney.
  • Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
  • Female who is pregnant or nursing
  • Constant drug use
  • Received facial laser therapy, chemical peeling or UV overexposure (>3 hours everyday) in the past 4 weeks.
  • Students taught by the PI
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
60 participants (actual)

Study arms

  • Placebo comparator
    Placebo drink

    Dietary Supplement: Placebo drink

  • Experimental
    Collagen drink

    Dietary Supplement: Collagen Juice Drink

Interventions

  • Dietary supplementPlacebo drink

    Blank

  • Dietary supplementCollagen Juice Drink

    Testing product

    Also known as: LISAVEI® Collagen Juice Drink

06

What researchers measure

Primary outcomes

  1. The change of skin wrinkles

    VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units

    Time frame: Change from Baseline skin wrinkles at 8 weeks

  2. The change of skin texture

    VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

    Time frame: Change from Baseline skin texture at 8 weeks

  3. The change of skin collagen density

    DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units

    Time frame: Change from Baseline skin collagen density at 8 weeks

  4. The change of skin elasticity

    Cutometer® MPA580 was utilized to measure skin elasticity. Units: arbitrary units

    Time frame: Change from Baseline skin elasticity at 8 weeks

  5. The change of skin L* value

    Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100

    Time frame: Change from Baseline L* value at 8 weeks

  6. The change of sleep quality

    Self-assessment questionnaire was utilized to survey sleep quality.

    Time frame: Change from Baseline sleep quality at 8 weeks

  7. The change of AGEs of blood

    Venous blood was sampled to measure AGEs

    Time frame: Change from Baseline AGEs at 8 weeks

  8. The change of TIMP-1 of blood

    Venous blood was sampled to measure TIMP-1

    Time frame: Change from Baseline TIMP-1 at 8 weeks

  9. The change of desmosine of blood

    Venous blood was sampled to measure desmosine

    Time frame: Change from Baseline desmosine at 8 weeks

Secondary outcomes

  1. The change of skin melanin index

    Soft Plus was utilized to measure skin melanin index. Units: arbitrary units

    Time frame: Change from Baseline skin melanin index at 8 weeks

  2. The change of skin pores

    VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units

    Time frame: Change from Baseline skin pores at 8 weeks

  3. The change of skin a* value

    Chroma Meter MM500 was utilized to measure skin a\* value. Units: arbitrary units

    Time frame: Change from Baseline skin a* value at 8 weeks

  4. The change of skin hydration

    Corneometer® CM825 was utilized to measure skin hydration. Units: arbitrary Corneometer® units 0-120

    Time frame: Change from Baseline skin hydration at 8 weeks

  5. The change of transepidermal water loss

    Tewameter® TM300 was utilized to measure skin hydration. Units: g/hm²

    Time frame: Change from Baseline transepidermal water loss at 8 weeks

07

Study locations

1 site
  • Chia Nan University of Pharmacy & Science
    Tainan, 71710, Taiwan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 13, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05182814
Lead sponsor
TCI Co., Ltd.
Responsible party
Sponsor
First posted
Jan 10, 2022
Start date
Nov 10, 2021
Primary completion
Feb 28, 2022
Completion
Apr 30, 2022
Last update
Jun 13, 2022

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.

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