An interventional study of Nefopam in Lung Cancer, sponsored by Kangbuk Samsung Hospital. Completed at 1 site in Korea, Republic of. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-02-14.
Sponsored by Kangbuk Samsung Hospital · Not applicable, Interventional, and Prevention
Acute postoperative pain after video-assisted thoracoscopic surgery is very severe. Because pain after thoracic surgery prevents early recovery, and increases postoperative complications, its is important to prevent pain after video-assisted thoracoscopic surgery. In the present study, we will evaluate whether nefopam reduces pain after video-assisted thoracoscopic surgery.
Kangbuk Samsung Hospital is the lead sponsor of 59 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Nefopam will not be administered in this group.
Intravenous nefopam 20 mg will be administered twice, immediately after induction of anesthesia and at the end of surgery.
Drug: Nefopam
Nefopam 20 mg is mixed to 100 mL of normal saline, and is infused intravenously over 15 minutes. 20 mg of nefopam is administered intravenously for two times, after induction and at the end of surgery.
Pain after 1 hour of surgery
Acute postoperative pain will be assessed using numerical rating scale from 0 (no pain) to 10 (worst pain ever).
Time frame: 1 hour after surgery.
Pain after 6 hour of surgery
Acute postoperative pain will be assessed using numerical rating scale from 0 (no pain) to 10 (worst pain ever).
Time frame: 6 hours hours after surgery.
Pain after 12 hour of surgery
Acute postoperative pain will be assessed using numerical rating scale from 0 (no pain) to 10 (worst pain ever).
Time frame: 12 hours after surgery.
Pain after 24 hour of surgery
Acute postoperative pain will be assessed using numerical rating scale from 0 (no pain) to 10 (worst pain ever).
Time frame: 24 hours after surgery.
Patient-controlled analgesia use
Fentanyl consumption administered thorough the patient-controlled analgesia machine.
Time frame: 24 hours after surgery
Rescue analgesics
Additional analgesic use during postoperative period.
Time frame: 24 hours after surgery.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.
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Kangbuk Samsung Hospital