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CompletedNCT05156411KREHAUpdated Aug 24, 2022

Strength Training With Eccentric Arm-cranking

An interventional study of eccentric arm-cranking training in Strength Training, sponsored by Swiss Paraplegic Research, Nottwil. Completed at 1 site in Switzerland. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-08-24.

Sponsored by Swiss Paraplegic Research, Nottwil · Not applicable, Interventional, and Basic science

From the registry’s dates

  • Registered 4 months after the study started (first participant enrolled Jul 2021, registered Nov 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
14
Allocation
Not applicable
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The new training device, the eccentric arm-crank, will be examined for its training effect by this project. That the training device can be used in athletes and patients with paraplegia in the future, the so-called "testing of the applicability of this concept" will be carried out during this study. Fourteen volunteer, healthy and trained people are first tested for their upper body performance, followed by a training phase over 20 trainings and at the and the performance data is collected again. The training intensity and duration is continuously increased during the training phase.

Read the detailed description

At the beginning, the study design includes an familiarisation appointment with performance tests and training on the eccentric arm-crank device (KREHA). At least one week later, the first test sequence including a maximum strength test (bench press), magnetic resonance imaging (MRI) to determine the muscle cross-section area of the upper arm and a test to determine the anaerobic performance (Wingate test) is conducted. The second test sequence takes place one to three days later. This includes a handgrip strength test, an aerobic endurance test (ramp test on the arm crank ergometer with ergospirometry) and a further familiarisation training on the KREHA. The training phase starts within two weeks after the pre-tests have been completed. There are two to a maximum of three trainings per week. These take 30 to 60 minutes and take place on the KREHA device under the supervision of the study staff. The training phase lasts a maximum of twelve weeks (20 training sessions). The first test sequence is repeated five to eight days after the last workout. The second test sequence takes place at the same time interval as in the pre-tests.

02

Conditions studied

  • Strength Training

Keywords

  • eccentric
03

In context

Lead sponsor

Swiss Paraplegic Research, Nottwil is the lead sponsor of 69 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • male or female
  • age between 18 and 50 years
  • experience in strength training
  • trained (minimum two times a week)
  • healthy
  • adequately informed and confirmed per signature

Exclusion criteria

Exclusion Criteria:

  • findings during anamnesis of study doctor
  • pregnancy
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
14 participants (actual)

Study arms

  • Experimental
    Eccentric Training

    This Group will train on the KREHA for 20 Trainings

    Other: eccentric arm-cranking training

Interventions

  • Othereccentric arm-cranking training

    Over the twenty training sessions, able-bodied participants will exercise on the KREHA device. An arm-crank has to be decelerated, which will be rotated by a prematurely defined revolution rate and training duration. During this intervention a certain power has to be applied. During the whole time of training a continous progression in power and training duration is applied

06

What researchers measure

Primary outcomes

  1. Upper body Performance

    Peak Power - maximal reached power, generated during the 30sec Wingate arm-crank test

    Time frame: through study completion, an average of 20 weeks

Secondary outcomes

  1. Endurance Oxygen consumption

    VO2peak \[ml/min/kg\] - Basic Endurance test (Ergospirometry, arm-crank)

    Time frame: through study completion, an average of 20 weeks

  2. Endurance Power

    Wmax \[W\] - Basic Endurance test (Ergospirometry, arm-crank)

    Time frame: through study completion, an average of 20 weeks

  3. Upper body Mean Power

    Mean Power \[W\] - Wingate Test (arm-crank)

    Time frame: through study completion, an average of 20 weeks

  4. Upper body Power - Time to Peak

    Time to Peak \[s\] - Wingate Test (arm-crank)

    Time frame: through study completion, an average of 20 weeks

  5. Upper body Fatigue resistance

    Fatigue Index \[%\]- Wingate Test (arm-crank)

    Time frame: through study completion, an average of 20 weeks

  6. Upper body Fatigue resistance

    Fatigue Slope \[W/s\] - Wingate Test (arm-crank)

    Time frame: through study completion, an average of 20 weeks

  7. 1RM bench press

    One Repetition Maximum (1RM) \[kg\]- bench press

    Time frame: through study completion, an average of 20 weeks

  8. Grip Strength

    Maximal Force that can be generated by pressing hand towards a fist \[N\]

    Time frame: through study completion, an average of 20 weeks

  9. Cross sectional muscle area

    Cross sectional area of the upper arm is measured with MRI

    Time frame: through study completion, an average of 20 weeks

  10. Upper Arm Circumference

    Circumference of the upper arm is measured with measuring tape

    Time frame: through study completion, an average of 20 weeks

07

Study locations

1 site
  • Swiss Paraplegic Centre
    Nottwil, Lucerne 6207, Switzerland
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 24, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05156411
Lead sponsor
Swiss Paraplegic Research, Nottwil
Responsible party
Sponsor
First posted
Dec 14, 2021
Start date
Jul 1, 2021
Primary completion
Feb 15, 2022
Completion
Mar 1, 2022
Last update
Aug 24, 2022

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Nov 2021. You cannot join it, but the record below documents what was studied.

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