CClinicalTrials.gg
Status unknownNCT05109897Updated Nov 5, 2021

Influencing Factors on Gait Variability in PD

An observational study in Parkinson Disease, sponsored by National Yang Ming Chiao Tung University. Status unknown at 1 site in Taiwan. Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2021-11-05.

Sponsored by National Yang Ming Chiao Tung University · Observational

The sponsor has not verified this record recently (last verified Oct 2021), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
100
Ages
40 Years to 80 Years
Sex
All
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Study summary

The principal motor features of Parkinson's disease (PD) include rigidity, tremor, bradykinesia, and postural instability. These motor deficits might cause gait dysfunction including reduced gait velocity, stride length, arm swing, and increased gait variability. Among these, increase in gait variability increased fall risk and served as a marker of disease progression. Previous studies reported that some factors might influence gait variability. However, which one contributes most has not yet been verified. Therefore, the purpose of the present study is to identify the more related influencing factors on gait variability in people with PD.

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Conditions studied

  • Parkinson Disease

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Keywords

  • Parkinson's disease, Gait variability
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In context

Parkinson Disease

4,487 studies on the registry are indexed under Parkinson Disease; 1,082 are open to participants now.

This study's planned enrollment of 100 is close to the median of 96 across 1,057 observational studies indexed under Parkinson Disease.

Browse Parkinson Disease studies →

Lead sponsor

National Yang Ming Chiao Tung University is the lead sponsor of 201 studies on the registry; 58 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
40 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

People with Parkinson's disease

Inclusion criteria

  • Idiopathic PD
  • Hoehn and Yahr stages I through III
  • Ability to stand and walk 5 m independently with or without any walking aids
  • Stable medication usage

Exclusion criteria

Exclusion Criteria:

  • Unstable medical conditions
  • Any neurological, cardiopulmonary or orthopedic problem/diseases that may interfere with participating the study
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Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
100 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Gait variability

    Using GAITRite system to measure coefficient of variation

    Time frame: 10 minutes

  2. Walking speed

    Using GAITRite system to evaluate

    Time frame: 10 minutes

  3. Sensory organization test

    Using NeuroCom Smart Balance Master to measure

    Time frame: 20 minutes

  4. Part III of the Unified Parkinson's Disease Rating Scale

    The score ranged from 0 to 72. Higher scores show increased severity.

    Time frame: 20 minutes

  5. Tinetti Balance Scale

    The score ranged from 0 to 28. Higher scores show better balance.

    Time frame: 10 minutes

  6. New freezing of gait questionnaire

    The score ranged from 0 to 29. Higher scores show increased severity in freezing of gait.

    Time frame: 15 minutes

  7. Montreal Cognitive Assessment

    The score ranged from 0 to 30. Higher scores show better cognitive function.

    Time frame: 20 minutes

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Study locations

1 site
  • Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
    Taipei, 112, Taiwan
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 5, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05109897
Lead sponsor
National Yang Ming Chiao Tung University
Responsible party
Yea-Ru Yang (Professor, National Yang Ming Chiao Tung University) — Principal investigator
First posted
Nov 5, 2021
Start date
Nov 1, 2021 (estimated)
Primary completion
Dec 31, 2022 (estimated)
Completion
Dec 31, 2022 (estimated)
Last update
Nov 5, 2021

Study contacts

Yea-Ru Yang, PhD
Contact
yryang@nycu.edu.tw
886228267279

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Oct 2021. You cannot join it, but the record below documents what was studied.

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