An observational study in ST-Segment Elevated Myocardial Infarction, sponsored by RenJi Hospital. Completed at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2021-11-04.
Sponsored by RenJi Hospital · Observational
The study intends to investigate the alteration of regional myocardial work in patients with acute anterior myocardial infarction underwent primary percutaneous coronary intervention (PCI), and compare the distribution of regional myocardial work in patients with/without early remodeling at acute phase and 3-month follow-up.
2,744 studies on the registry are indexed under Myocardial Infarction; 418 are open to participants now.
This study's enrollment of 98 is below the median of 500 across 983 observational studies indexed under Myocardial Infarction.
Browse Myocardial Infarction studies →RenJi Hospital is the lead sponsor of 535 studies on the registry; 244 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with anterior STEMI who underwent primary PCI \<12 hours after symptom onset were consecutive enrolled in our center.
Exclusion Criteria:
Delta-work efficiency by echocardiography
A novel tool for non-invasive myocardial work(MW) assessment has been introduced to evaluate myocardial performance.MW was calculated as a function of time through a combination of LV global longitudinal strain(GLS) data and an estimated LV pressure curves. Work efficiency (WE) was calculated from the ratio of the constructive work to the sum of constructive and wasted work, expressed as a percentage.The values of culprit regional WE was expressed as WE-LAD.The values of non-culprit regional WE was expressed as WE-nonLAD.The absolute differences of the WE was calculated as the values of non-culprit regional WE minus the values of culprit regional WE, and noted as delta-WE.
Time frame: 24-72 hours after PCI
Global work index by echocardiography
Global work index (GWI) is classified as total work within the area of the LV pressure-strain loop calculated from mitral valve closure to mitral valve opening.
Time frame: 24-72 hours, 3-month after PCI
Global constructive work by echocardiography
Global constructive work (GCW) was defined as work contributing to LV ejection performed during shortening in systole and work performed during lengthening in isovolumic relaxation.
Time frame: 24-72 hours, 3-month after PCI
Global work efficiency by echocardiography
Global work efficiency (GWE) was calculated from the ratio of the constructive work to the sum of constructive and wasted work, expressed as a percentage.
Time frame: 24-72 hours, 3-month after PCI
Work index-LAD
Work index in left anterior descending(LAD) territory.
Time frame: 24-72 hours, 3-month after PCI
Constructive work-LAD
constructive work in left anterior descending(LAD) territory.
Time frame: 24-72 hours, 3-month after PCI
Work efficiency-LAD
Work efficiency in left anterior descending(LAD) territory.
Time frame: 24-72 hours, 3-month after PCI
Plan to share: Undecided
This study is completed, as verified in Oct 2021. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
RenJi Hospital