An observational study in Cancer of Stomach, Cancer of Esophagus and Malnutrition, sponsored by Jinling Hospital, China. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-10-21.
Sponsored by Jinling Hospital, China · Observational
The present study aims to investigate the prognostic value of preoperative fat-free mass index for postoperative outcomes in patients undergoing esophagogastric cancer surgery, and to explore the role of the FFMI in the Global Leadership Initiative on Malnutrition (GLIM) criteria.
The GLIM criteria of malnutrition as a consensus lack of optimal combination in clinical validation. After the publication of the GLIM consensus, few studies have examined the effect of reduced FFMI on the clinical prognosis of patients with esophagogastric cancer, and whether the FFMI can be used as an effective diagnostic criterion of malnutrition in esophagogastric cancer needs to be further studied.
Therefore, the present study aims were to investigate the prognostic value of preoperative fat-free mass index for postoperative outcomes in patients undergoing esophagogastric cancer surgery, and to explore the role of the FFMI in the GLIM consensus for malnutrition.
1,593 studies on the registry are indexed under Esophageal Neoplasms; 461 are open to participants now.
This study's enrollment of 205 is close to the median of 200 across 341 observational studies indexed under Esophageal Neoplasms.
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Elective surgery for esophagogastric cancer (there was a clear pathological diagnosis before surgery)
Elective surgery for esophagogastric cancer (there was a clear pathological diagnosis before surgery); NRS2002≥3; Preoperative BIA examination was performed.
Exclusion Criteria:
Discharged from a hospital within 24 hours; No BIA examination and not suitable for BIA examination (such as ascites, edema, amputation and pace-maker); Hepatic insufficiency (alanine transaminase/aspartate transaminase ratio 200% above normal range or bilirubin>3mg/dL) ; Renal insufficiency (serum creatinine>1.5mg/dL); Emergency operation; Pregnancy; Missing the postoperative information follow-up data.
The FFMI was calculated as follows: FFMI = fat-free mass (kg)/height squared (m2). FFMI cut-off values (derived from BIA measurements, \</≥15 kg/m2 for females and \</≥17 kg/m2 for males). Patients with esophagogastric cancer were then divided into the normal FFMI group (FFMI ≥17 kg/m2 for male and FFMI ≥15 kg/m2 for female).
Other: no intervention
The FFMI was calculated as follows: FFMI = fat-free mass (kg)/height squared (m2). FFMI cut-off values (derived from BIA measurements, \</≥15 kg/m2 for females and \</≥17 kg/m2 for males). Patients with esophagogastric cancer were then divided into the low FFMI group (FFMI \<17 kg/m2 for male and FFMI \<15 kg/m2 for female).
Other: no intervention
postoperative complications
postoperative complications (infectious complications and noninfectious complications)
Time frame: Within 60 days after surgery
length of stay (LOS)
length of stay (LOS)
Time frame: Within 60 days after surgery
wound healing time
wound healing time
Time frame: Within 60 days after surgery
postoperative antibiotic time
postoperative antibiotic time
Time frame: Within 60 days after surgery
nutritional status
nutritional status ( such as: weight，albumin，prealbumin)
Time frame: up to 4 weeks
hospitalization cost
hospitalization cost(including: surgery and medicine costs)
Time frame: Within 60 days after surgery
No study locations are listed for this record.
This study is completed, as verified in Oct 2021. You cannot join it, but the record below documents what was studied.
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Jinling Hospital, China