A Phase 4 interventional study of standard pain relievers in Knee Injuries, sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche. Terminated at 1 site in France. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-05-16.
Sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche · Phase 4, Interventional, and Prevention
Interventional, comparative, randomized, controlled study versus standard treatment, in 3 parallel groups, monocentric, aiming to demonstrate the superiority of preoperative cryoneurolysis versus no procedure, in patients operated on for knee arthroplasty and receiving standard analgesia.
249 studies on the registry are indexed under Knee Injuries; 48 are open to participants now.
This study's enrollment of 52 is close to the median of 50 across 160 interventional studies indexed under Knee Injuries.
Browse Knee Injuries studies →GCS Ramsay Santé pour l'Enseignement et la Recherche is the lead sponsor of 198 studies on the registry; 94 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
A cryoneurolysis of the saphenous nerve will be performed between 7 days and 5 days before the knee arthroplasty
Drug: standard pain relievers
A cryoneurolysis of geniculate nerves will be performed between 7 days and 5 days before the knee arthroplasty
Drug: standard pain relievers
No cryoneurolysis will be performed before the knee arthroplasty
Drug: standard pain relievers
Knee arthroscopy will be performed ansd patients will receive standard pain relievers in confomtity with the current practice
Also known as: Standard pain relievers in accordance with the current practice
90 ° flexion pain 2 days after the arthroscopy
Evaluation of the knee pain at 90° flexion with a visual analogic scale of 100 mm
Time frame: 2 days
90 ° flexion pain 1 day after the arthroscopy
Evaluation of the knee pain at 90° flexion with a visual analogic scale of 100 mm
Time frame: 1 day
90 ° flexion pain 7 days after the arthroscopy
Evaluation of the knee pain at 90° flexion with a visual analogic scale of 100 mm
Time frame: 7 days
90 ° flexion pain 30 days after the arthroscopy
Evaluation of the knee pain at 90° flexion with a visual analogic scale of 100 mm
Time frame: 30 days
90 ° flexion pain 90 days after the arthroscopy
Evaluation of the knee pain at 90° flexion with a visual analogic scale of 100 mm
Time frame: 90 days
pain at rest at Day 1
Knee pain after intervention with a visual analogic scale of 100 mm
Time frame: 1 day
pain at rest at Day 2
Knee pain after intervention with a visual analogic scale of 100 mm
Time frame: 2 days
pain at rest at Day 7
Knee pain after intervention with a visual analogic scale of 100 mm
Time frame: 7 days
pain at rest at Day 30
Knee pain after intervention with a visual analogic scale of 100 mm
Time frame: 30 days
pain at rest at Day 90
Knee pain after intervention with a visual analogic scale of 100 mm
Time frame: 90 days
Plan to share: No
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This study is terminated, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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GCS Ramsay Santé pour l'Enseignement et la Recherche