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CompletedNCT04968327Updated Jul 20, 2021

Micro-osteoperforations on the Rate of Canine Retraction

An interventional study of Micro-osteoperforations (MOPs) and Conventional canine retraction in Malocclusion, sponsored by Hams Hamed Abdelrahman. Completed at 1 site in Egypt. Open to participants aged 15 Years to 20 Years. Per ClinicalTrials.gov, last updated 2021-07-20.

Sponsored by Hams Hamed Abdelrahman · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 4 years 6 months after the study started (first participant enrolled Jan 2017, registered Jul 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
10
Allocation
Randomized
Ages
15 Years to 20 Years
Sex
All
01

Study summary

the study aimed to clinically evaluate the effect of micro-osteoperforations on the rate of tooth movement, as evaluated by its effect on the rate of canine retraction.

Read the detailed description

Ten adult patients requiring maxillary first premolars' extraction were enrolled in this split-mouth randomized controlled clinical trial.

Micro-osteoperforations were randomly assigned to one side of the maxillary arch at the canine-premolar region, and the contralateral side served as the control.

Mini-screws were used for anchorage reinforcement, and canine retraction was performed using nickel-titanium closed coil springs, delivering a force of 150 grams per side.

The primary outcome was the measurement of canine retraction rate throughout the study period from digital dental models obtained every 3 weeks.

The secondary outcome was the detection of possible canine tipping during retraction.

02

Conditions studied

  • Malocclusion

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03

In context

Malocclusion

457 studies on the registry are indexed under Malocclusion; 89 are open to participants now.

This study's enrollment of 10 is below the median of 36 across 372 interventional studies indexed under Malocclusion.

Browse Malocclusion studies →

Lead sponsor

Hams Hamed Abdelrahman is the lead sponsor of 107 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 20 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • healthy systemic condition with no chronic diseases
  • no previous orthodontic treatment
  • adequate oral hygiene
  • have a healthy periodontium
  • signed an informed consent

Exclusion criteria

Exclusion Criteria:

  • have a chronic disease
  • previous orthodontic treatment
  • poor oral hygiene or periodontal conidition
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
10 participants (actual)

Study arms

  • Experimental
    Micro-osteoperforations

    Other: Micro-osteoperforations (MOPs) · Other: Conventional canine retraction

  • Active comparator
    Canine retraction

    Other: Conventional canine retraction

Interventions

  • OtherMicro-osteoperforations (MOPs)

    MOPs included shallow perforations of the buccal cortical plate surrounding the tooth that requires orthodontic tooth movement, with no flap reflection was performed using a surgical bur using the special calibrated device called PROPEL

  • OtherConventional canine retraction

    using nickel-titanium (NiTi) closed coil-springs delivering a force of 150 grams per side

06

What researchers measure

Primary outcomes

  1. Rate of canine retraction

    measurements were recorded from digital dental models every 3 weeks

    Time frame: 12 weeks

Secondary outcomes

  1. Measurment of canine tipping

    Tipping of the maxillary canine during retraction was also evaluated from digital dental models

    Time frame: 12 weeks

07

Study locations

1 site
  • Alexandria Faculty of Dentistry
    Alexandria, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 20, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04968327
Lead sponsor
Hams Hamed Abdelrahman
Responsible party
Hams Hamed Abdelrahman (Assistant lecturer of DPH and Clinical statistician, Alexandria University) — Sponsor-investigator
First posted
Jul 20, 2021
Start date
Jan 1, 2017
Primary completion
Aug 18, 2017
Completion
Aug 30, 2017
Last update
Jul 20, 2021

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.

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