ClinicalTrials.gg
Status unknownNCT04952103Updated Jul 7, 2021

Real World Study of Diagnosis and First-line Treatment Among Patients With Cancer of Unknown Primary in China

An observational study in Cancer of Unknown Primary Site, sponsored by Fudan University. Status unknown at 1 site in China. Per ClinicalTrials.gov, last updated 2021-07-07.

Sponsored by Fudan University · Observational

The sponsor has not verified this record recently (last verified Jun 2021), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Sex
All
01

Study summary

This study is a prospective, real world study.The objective is to observe the diagnosis and first-line treatment of Chinese patients with cancer of unknown primary, and collect the clinicopathological characteristics, treatment outcomes, survival and other data of the patients.

02

Conditions studied

  • Cancer of Unknown Primary Site
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In context

Neoplasms, Unknown Primary

101 studies on the registry are indexed under Neoplasms, Unknown Primary; 19 are open to participants now.

This study's planned enrollment of 200 is above the median of 125 across 25 observational studies indexed under Neoplasms, Unknown Primary.

Browse Neoplasms, Unknown Primary studies →

Lead sponsor

Fudan University is the lead sponsor of 1,315 studies on the registry; 643 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with cancer of unknown primary (CUP) and are gonging to receive the first-line therapy for CUP

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Had a diagnosis of cancer of unknown primary (CUP) after a standard evaluation .
  • Prepared to receive therapy for CUP

Exclusion criteria

Exclusion Criteria:

  • Patients who had previously received systemic therapy for CUP
  • Previous history of other cancers, except cervix cancer or basal cell carcinoma of the skin that has been cured
  • The investigator considered that there were to treatment or were not appropriate to participate in this study
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Line of therapy

A line of therapy is one course of treatment, which may combine several drugs. First-line is the first course given; second-line follows when that stops working or is not tolerated.

“Two prior lines” means two courses that count separately under the study’s rules — not simply two drugs. Ask the study team if you are unsure how yours are counted.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (estimated)
Patient registry
No

Interventions

  • Otherno intervention

    The patient's treatment is determined by the physician in charge according to the patient's clinical situation and relevant guidelines, without additional intervention.

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What researchers measure

Primary outcomes

  1. Progression-free survival (PFS)

    Time frame: 8 months

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Study locations

1 of 1 sites recruiting
  • Fudan University Shanghai Cencer Center
    Shanghai, Shanghai 200032, China
    Recruiting
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jun 2021 (actual). Primary completion is estimated for Jun 2023, 24 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 30, 2021
First posted
Jul 7, 2021
StartActual
Jun 18, 2021
Primary completionEst.
Jun 18, 2023
CompletionEst.
Jun 18, 2024
Last update
Jul 7, 2021
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 7, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04952103
Lead sponsor
Fudan University
Responsible party
Zhiguo Luo, MD, PhD (Professor, Fudan University) — Principal investigator
First posted
Jul 7, 2021
Start date
Jun 18, 2021
Primary completion
Jun 18, 2023 (estimated)
Completion
Jun 18, 2024 (estimated)
Last update
Jul 7, 2021

Study contacts

Xin Liu
Contact
jeanettexin@hotmail.com
13761503356

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2021. You cannot join it, but the record below documents what was studied.

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Discussion

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