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CompletedNCT04941677Updated Apr 3, 2024

Exploring Hand Function in People With Schizophrenia Based on Perspective of Sensorimotor Control

An observational study in Schizophrenia, sponsored by National Cheng-Kung University Hospital. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-04-03.

Sponsored by National Cheng-Kung University Hospital · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
37
Ages
20 Years to 65 Years
Sex
All
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Study summary

The study aims to explore the hand function in people with schizophrenia in the chronic stage.

02

Conditions studied

  • Schizophrenia

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Keywords

  • hand function
  • sensorimotor
  • motor control theory
03

In context

Schizophrenia

3,539 studies on the registry are indexed under Schizophrenia; 473 are open to participants now.

This study's enrollment of 37 is below the median of 178 across 503 observational studies indexed under Schizophrenia.

Browse Schizophrenia studies →

Lead sponsor

National Cheng-Kung University Hospital is the lead sponsor of 276 studies on the registry; 71 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 65 Years
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Participants with schizophrenia will be recruited from the Department of Internal Medicine in National Cheng Kung University Hospital

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age between 20-65 years old
  • Diagnosis with schizophrenia or schizoaffective disorder by psychiatrists according to DSM5.
  • Remaining the same antipsychotics and the symptom was stable for at least one month before the study.
  • Be able to follow comments and have sufficient cognitive ability assessed by Mini-Mental State Examination score >24

Exclusion criteria

Exclusion Criteria:

  • Substance abuse or other medical conditions that may affect movements.
  • Using other non-antipsychotics that will affect movements in the same period.
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
37 participants (actual)
Target follow-up
1 Month
Patient registry
Yes

Groups and cohorts

  • schizophrenia group

    No intervention age between 20-65, diagnosed schizophrenia by DSM-5.

    Other: no intervention

Interventions

  • Otherno intervention

    no intervention in this study

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What researchers measure

Primary outcomes

  1. Semmes Weinstein Monofilaments

    Semmes Weinstein Monofilaments is used to assess cutaneous pressure thresholds.

    Time frame: baseline

  2. Pinch-holding-up-activity test

    The pinch apparatus is aims to assess the ability to modulate pinch force to movement-induced load fluctuations in a pinch-holding-up activity (PHUA).

    Time frame: baseline

  3. Manual Tactile Test

    Manual tactile test (MTT) aims to assess the capacity of barognosis, roughness differentiation and stereognosis.

    Time frame: baseline

  4. Purdue pegboard test

    The purpose for Purdue pegboard test is to measure manipulative dexterity including unimanual and bimanual hand dexterity.

    Time frame: baseline

  5. The Valpar 8 simulates assembly work assessment

    Valpar8 simulates the light work and assess the ability of manual dexterity and motor coordination.

    Time frame: baseline

Secondary outcomes

  1. Self-reported version of the graphic Personal and Social Performance (SRG-PSP)

    The self-reported version of the graphic personal and social performance is a self-report scale that aims to assess functional performance.

    Time frame: baseline

07

Study locations

1 site
  • National Cheng-Kung University
    Tainan, 701, Taiwan
08

References and documents

Publications

  • Lai YJ, Lin YC, Hsu CH, Tseng HH, Lee CN, Huang PC, Hsu HY, Kuo LC. Are the sensorimotor control capabilities of the hands the factors influencing hand function in people with schizophrenia? BMC Psychiatry. 2023 Nov 7;23(1):807. doi: 10.1186/s12888-023-05259-w. PubMed 37936136 ↗
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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Sep 2020 to primary completion in Jul 2022, 22 months.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 20, 2021
First posted
Jun 28, 2021
StartActual
Sep 17, 2020
Primary completionActual
Jul 31, 2022
CompletionActual
Dec 31, 2022
Last update
Apr 3, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 3, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04941677
Responsible party
Sponsor
First posted
Jun 28, 2021
Start date
Sep 17, 2020
Primary completion
Jul 31, 2022
Completion
Dec 31, 2022
Last update
Apr 3, 2024

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.

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