An interventional study of Dorsal wrist ganglion alone (DWG) and DWG/PIN in Wrist Ganglion, Ganglion Cysts and Hand Ganglion, sponsored by Kenneth Taylor, M.D.. Terminated at 2 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-11.
Sponsored by Kenneth Taylor, M.D. · Not applicable, Interventional, and Treatment
The purpose of this study is to determine if a statistical significance exists between outcomes of patients treated for dorsal wrist ganglion cyst with excision alone versus excision and the addition of a partial wrist denervation by resecting the common terminal sensory branch of the PIN (posterior interosseus nerve). Our hypothesis is that addition of PIN improves outcome after dorsal wrist ganglion excision as indicated by post-operative pain, function, ability to perform activities of daily living, and physical exam findings.
The primary endpoint will be outcomes on subject surveys and questionnaires. Data will be collected pre- and post-operatively at 2 weeks, 12 weeks, 6 months, and one year. Four questionnaires will be used, including the Visual Analog Pain Score (VAS), Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire, as well as the Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference (PI), and the PROMIS Pain Behavior (PB) questionnaires.
Secondary outcomes include physical examination consisting of pre- and post-operative pinch and grip strength testing, and active range of motion including wrist flexion and extension ulnar and radial deviation, and weight bearing extension. These will be performed at 2 weeks, 12 weeks, and 6 months post-operatively.
136 studies on the registry are indexed under Ganglion Cysts; 28 are open to participants now.
This study's enrollment of 3 is below the median of 60 across 101 interventional studies indexed under Ganglion Cysts.
Browse Ganglion Cysts studies →Kenneth Taylor, M.D. is the lead sponsor of 3 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Dorsal wrist ganglion excision alone
Procedure: Dorsal wrist ganglion alone (DWG)
Dorsal wrist ganglion excision with posterior interosseus neurectomy (PIN)
Procedure: DWG/PIN
Patients assigned to this arm will undergo dorsal wrist ganglion cyst excision alone.
Patients assigned to this arm will undergo dorsal wrist ganglion excision and the addition of a partial wrist denervation by resecting the common terminal sensory branch of the posterior interosseus nerve (PIN)..
Pain measured with the Visual Analog Pain Scale (VAS)
Self-report measurement that assesses a person's perceived level of pain
Time frame: Preop to One Year Post-Op
Physical Function measured with the Disabilities of the Arm, Shoulder and Hand questionnaire (QuickDASH)
11-Item questionnaire that measures physical function and symptoms in people with musculoskeletal disorders of the upper limb
Time frame: Preop to One Year Post-Op
Pain interference measured with the Patient-Reported Outcomes Measurement Information (PROMIS) Pain Interference instrument
This instrument measures the self-reported consequences of pain on relevant aspects of one's life and may include the extent to which pain hinders engagement with social, cognitive, emotional, physical, and recreational activities.
Time frame: Preop to One Year Post-Op
Pain behavior measured with the Patient-Reported Outcomes Measurement Information (PROMIS) Pain Behavior instrument
This instrument measures self-reported external manifestations of pain: behaviors that typically indicate to others that an individual is experiencing pain.
Time frame: Preop to One Year Post-Op
Change in strength utilizing hand grip measurements
This measurement provides information about muscle strength health in the hand and forearms. The average of three measurements is taken using a hand-held dynamometer
Time frame: Preop to 6 Months Post-Op
Change in strength utilizing finger lateral pinch measurements
This measurement provides information about the functional strength of one's pinching action of the hand using a mechanical pinch gauge. The average of three measurements will be taken at each time frame.
Time frame: Preop to 6 Months Post-Op
Change in strength utilizing finger tip pinch measurements
This measurement provides information about the functional strength of one's pinching action of the hand using a mechanical pinch gauge. The average of three measurements will be taken at each time frame.
Time frame: Preop to 6 Months Post-Op
Change in strength utilizing finger three-point pinch measurements
This measurement provides information about the functional strength of one's pinching action of the hand using a mechanical pinch gauge. The average of three measurements will be taken at each time frame.
Time frame: Preop to 6 Months Post-Op
Change in wrist flexion
This measurement indicates the range of motion of the wrist utilizing a goniometer
Time frame: Preop to 6 Months Post-Op
Change in wrist extension
This measurement indicates the range of motion of the wrist utilizing a goniometer
Time frame: Preop to 6 Months Post-Op
Change in wrist weight bearing extension
This measurement indicates the range of motion of the wrist utilizing a goniometer
Time frame: Preop to 6 Months Post-Op
Change in wrist ulnar deviation
This measurement indicates the range of motion of the wrist from side to side. This movement flexes the hand toward the ulnar bone in the arm. This is measured with a goniometer.
Time frame: Preop to 6 Months Post-Op
Change in wrist radial deviation
This measurement indicates the range of motion of the wrist from side to side. This movement flexes the hand toward the radial bone in the arm. This is measured with a goniometer.
Time frame: Preop to 6 Months Post-Op
This study is terminated, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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