An observational study in Allergic Rhinitis, Allergic Asthma and Pollution; Exposure, sponsored by Cindy Elizabeth de Lira-Quezada. Status unknown at 1 site in Mexico. Open to participants aged 6 Years and older. Per ClinicalTrials.gov, last updated 2021-05-26.
Sponsored by Cindy Elizabeth de Lira-Quezada · Observational
In Latin America and the Caribbean, more than 100 million people are exposed to higher levels of pollution than those recommended by WHO. The objective of the study is to determine the relationship between exposure to environmental pollutants and the prevalence and exacerbation of respiratory allergy. It is an observational, prospective, longitudinal and descriptive study that will include subjects older than 6 years who come to the consultation of the Regional Center for Allergy and Clinical Immunology with a diagnosis of respiratory allergy, positive skin tests and who live in Monterrey and its metropolitan area. After verbal assent, the subject's address and work area will be registered, the Rhinitis Control Assessment Test and the Asthma Control Test as well as spirometry will be made. The geolocation of industries and avenues near the address and work area of subjects will be carried out, as well as the determination of pollutants and pollens by the Integral Monitoring System (SIMA) and the Pollen Sense device. Subsequently, the correlation between exposure to pollutants and respiratory allergy will be analyzed. Dispersion models will be built considering pollutants and climatic factors (precipitation, wind speed, humidity and temperature). By carrying out this project, it will be possible to contribute to the identification of the factors that lead to the development and exacerbation of allergic respiratory diseases and subsequently propose the implementation of measures for their control and recommendations for prevention to the population.
1,105 studies on the registry are indexed under Rhinitis; 65 are open to participants now.
This study's planned enrollment of 93 is below the median of 141 across 172 observational studies indexed under Rhinitis.
Browse Rhinitis studies →This is the only study on the registry with Cindy Elizabeth de Lira-Quezada as lead sponsor.
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Subjects older than 6 years of age, who attend the Regional Center of Allergy and Clinical Immunology of the University Hospital "Dr. José Eleuterio González "with a diagnosis of respiratory allergy (allergic rhinitis and asthma) and type I immunological hypersensitivity demonstrated by skin tests performed by an allergist and who live in Monterrey or its metropolitan area.
They will be invited to participate in the protocol and if they agree to be included, they will respond to informed verbal consent or assent.
Exclusion Criteria:
Pollutants (ozone, SO3, NO3, PM2.5, diesel exhaust particles)
Association of respiratory symptoms with exposure to pollutants and pollen
To determine the relationship between exposure to environmental pollutants and the prevalence and exacerbation of respiratory allergy.
Time frame: 1 year
Avenues with highest diesel exhaust particles and traffic related particles
Locate the avenues with the highest flow and vehicular load releasing diesel removal particles (DEP) and traffic-related air pollutants (TRAP).
Time frame: 1 year
Location of the main industries that emit pollutants
Location of the main industries that emit pollutants of particulate matter (PM), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO) and ozone (O3).
Time frame: 1 year
Distance of greater exposure to pollutants
To assess the relationship between the distance to PM, traffic-related air pollutants (TRAP) and diesel exhaust particles (DEP) with the prevalence of respiratory allergy symptoms with home and work address.
Time frame: 1 year
Time of pollutant exposure and association with respiratory symptoms
Evaluate the relationship between the time of exposure to PM, NO2, SO2, O3, traffic-related air pollutants (TRAP) and diesel exhaust particles (DEP) with the prevalence of respiratory allergy symptoms.
Time frame: 1 year
Plan to share: No
This study is status unknown, as verified in May 2021. You cannot join it, but the record below documents what was studied.
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