An observational study in Frailty, sponsored by Dr. Valerie-Anna Rudas. Completed at 1 site in Austria. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-03-19.
Sponsored by Dr. Valerie-Anna Rudas · Observational
Frailty is a multifactorial condition associated with older age, which leads to increased vulnerability to external stressors, such as infections or surgical procedures. Key features of frailty are unintentional weight loss, reduced strength and physical activity as well as the feeling of exhaustion.
When selecting patients for surgery, frailty can play an important part in resource planning and prognostication. Multiple studies have shown frailty to have a negative impact on mortality, perioperative adverse events, hospital length of stay as well as postoperative quality of life and functional status. Despite it being an important patient-centered outcome, postoperative quality of life tends to be overlooked when selecting patients for surgery.
Cardiac surgery presents a massive stressor to the frail patient, but on the other hand might have the ability to reduce disease burden and improve functional status, thus reducing frailty.
This prospective observational cohort study aims to assess frailty, as well as functional status and quality of life in cardiosurgical patients pre- and postoperatively, and evaluate its impact on postoperative clinical and functional outcomes.
The primary endpoint of this study is the change in postoperative level of frailty.
1,199 studies on the registry are indexed under Frailty; 430 are open to participants now.
This study's enrollment of 80 is below the median of 223 across 496 observational studies indexed under Frailty.
Browse Frailty studies →This is the only study on the registry with Dr. Valerie-Anna Rudas as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Patients undergoing an elective cardiac surgical intervention
Exclusion Criteria:
Change in Postoperative Level of Frailty
The "Clinical Frailty Scale" (CFS) will be used to assess frailty. A CFS of 1 indicates absence of frailty, whereas a CFS of 9 indicates severe frailty. A postoperative change in the CFS indicates a postoperative change in frailty.
Time frame: 12 months
Quality of Life assessed by the "SF-12 Patient Questionnaire"
Quality of Life will be assessed using the SF-12 Patient Questionnaire.
Time frame: 12 months
Functional Status assessed by the "Functional Independence Measure"
Functional status will be assessed using the "Functional Independence Measure", with lower scores indicating a worse functional status.
Time frame: 12 months
30-day Mortality
Number of participants who have died within 30 days postoperatively.
Time frame: 30 days
Overall Mortality
Number of participants who have died within the study period.
Time frame: 12 months
This study is completed, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.
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