An interventional study of Pea-protein concentrate and Fava-bean protein concentrate in Bioavailability of Amino Acids Following Oral Ingestion of Plant-Based Proteins in Young, Healthy Men, sponsored by University of Limerick. Completed at 1 site in Ireland. Open to male participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-11-30.
Sponsored by University of Limerick · Not applicable, Interventional, and Other
This study aims to inform of the mechanism of action of plant-based protein by measuring the bioavailability (i.e. rate of appearance and magnitude of concentration in the circulation following oral ingestion) of key amino acid and metabolic products that regulate skeletal muscle protein synthesis (MPS) in humans.
Plant-based proteins contain several amino acids that are essential to signal muscle growth/repair and act as a substrate during muscle protein synthesis. However, compared to animal protein or free-amino acids, the bioavailability of certain essential amino acids may be compromised. Following selective processing (e.g. removal of carbohydrate and/or other anti-nutritive factors) food grade plant-based protein concentrates possibly confer greater bioavailability and bioactivity in vivo. This project explores the bioavailability and bioactivity of selected plant-based protein concentrates following oral ingestion in young, healthy men and women.
University of Limerick is the lead sponsor of 56 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Pea-protein concentrate dosed at 0.33 g/kg body mass in 500 ml of water.
Dietary Supplement: Pea-protein concentrate
Fava-bean protein concentrate dosed at 0.33 g/kg body mass in 500 ml of water.
Dietary Supplement: Fava-bean protein concentrate
Chickpea protein concentrate dosed at 0.33 g/kg body mass in 500 ml of water.
Dietary Supplement: Chickpea protein concentrate
Red lentil protein concentrate dosed at 0.33 g/kg body mass in 500 ml of water.
Dietary Supplement: Red lentil protein concentrate
Non-essential amino acid blend dosed at 0.33 g/kg body mass in 500 ml of water.
Dietary Supplement: Non-essential amino acid blend
Whey protein concentrate dosed at 0.33 g/kg body mass in 500 ml of water.
Dietary Supplement: Whey protein concentrate
Pea-protein concentrate
Fava-bean protein concentrate
Chickpea protein concentrate
Red lentil protein concentrate
Non-essential amino acid blend
Whey protein concentrate
Plasma amino acids
Plasma amino acids measured by HPLC
Time frame: 3 hours
This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of Limerick