ClinicalTrials.gg
CompletedNCT04862754Updated Mar 15, 2022

Effect of Interval Training on Arterial Stiffness in Women With Hypertension

An interventional study of interval training exercise in Arterial Stiffness, sponsored by Cairo University. Completed at 1 site in Egypt. Open to female participants aged 40 Years to 60 Years. Per ClinicalTrials.gov, last updated 2022-03-15.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
40 Years to 60 Years
Sex
Female
01

Study summary

this study is aiming to assess the chronic effect of the interval training program on arterial stiffness in women with hypertension

02

Conditions studied

  • Arterial Stiffness
03

In context

Lead sponsor

Cairo University is the lead sponsor of 4,911 studies on the registry; 1,443 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 60 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • physically inactive
  • BMI 30-40
  • Stage 1 and 2 hypertension
  • Elevated BP as systolic BP ≥130 mm Hg and/or diastolic BP ≥85 mm Hg measured at the brachial artery.

Exclusion criteria

Exclusion Criteria:

  • Medications known to affect weight or appetite
  • Any disease associated with exercise intolerance.
  • Women were taking hormone replacement therapy
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
50 participants (actual)

Study arms

  • Experimental
    interval training

    Aerobic interval training. It consisted of a modified interval cycle ergometer training program (3 days a week for 8 weeks). AIT consisted of 8 min warm up, followed by four times of 4-min intervals with HR at 80% of submaximal predetermined HR, with active phases of 3 min of cycling at 60% of submaximal predetermined HR. The exercise session was terminated by 5 min cool down

    Other: interval training exercise

  • No intervention
    medical treatment

    hypertensive medication

Interventions

  • Otherinterval training exercise

    interval training exercise

06

What researchers measure

Primary outcomes

  1. Central arterial stiffness measurements (Pulse Wave Velocity [PWV], augmentation index )

    Pulse wave analysis (PWA) of the women in the two groups: pre and post treatment for pulse wave velocity (PWV) and augmentation index(AIx) Pulse Wave Velocity \[PWV\], augmentation index (AIx @75HR) and resting heart rate were measured using analysis equipment which called Non-invasive blood pressure measurement system using "Mobil-O-Graph 24h PWA " with Hypertension Management Software Client Server (HMS-CS 4.3). PWA was performed using an oscillometric Mobil-O-Graph R 24 h PWA Monitor device (I.E.M GmbH, Germany) with integrated ARCSolver® software

    Time frame: two months

Secondary outcomes

  1. blood lipid profile

    blood analysis will be used to measure lipid profile (high and low-density lipoprotein, cholesterol, triglyceride)

    Time frame: two months

  2. interleukin 6

    blood analysis will be used to measure interleukin 6

    Time frame: two months

  3. blood pressure (systolic and diastolic)

    resting Blood pressure was monitored from the right arm using an automated digital electronic BP monitor (Omron digital BP monitor, Model 11 EM 403c; Tokyo Japan).

    Time frame: two months

07

Study locations

1 site
  • Faculty of physical therapy
    Cairo, 17452, Egypt
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jan 2021 to primary completion in Mar 2021, 2 months.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 12, 2021
First posted
Apr 28, 2021
StartActual
Jan 25, 2021
Primary completionActual
Mar 30, 2021
CompletionActual
Apr 15, 2021
Last update
Mar 15, 2022
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 15, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04862754
Lead sponsor
Cairo University
Responsible party
Mona Mohamed Taha (Cairo University, Cairo University) — Principal investigator
First posted
Apr 28, 2021
Start date
Jan 25, 2021
Primary completion
Mar 30, 2021
Completion
Apr 15, 2021
Last update
Mar 15, 2022

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.

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