An observational study in Myocarditis, sponsored by Assistance Publique - Hôpitaux de Paris. Recruiting at 1 site in France. Open to participants aged 15 Years and older. Per ClinicalTrials.gov, last updated 2025-06-06.
Sponsored by Assistance Publique - Hôpitaux de Paris · Observational
Among 13 studies in Myocarditis by Assistance Publique - Hôpitaux de Paris — 9 open to participants now, 9 under way, 2 of them phase 3. Myocarditis · Assistance Publique - Hôpitaux de Paris.
Among the 13 studies in Myocarditis by Assistance Publique - Hôpitaux de Paris, this one is one of 2 that started in 2022, is one of 6 observational ones, and was the 4th registered.
174 studies on the registry are indexed under Myocarditis; 75 are open to participants now.
This study's planned enrollment of 1,400 is above the median of 208 across 120 observational studies indexed under Myocarditis.
Browse Myocarditis studies →9 of the 13 studies in Myocarditis by Assistance Publique - Hôpitaux de Paris are open now, in 1 country. Each count lists the studies.
Of the 53 Myocarditis studies recruiting now, 31 (58%) set no upper age limit and 6 (11%) stop at 75 or younger; 15 take children under 18; 14 take healthy volunteers.
This study: 15 Years and older · all sexes · no healthy volunteers.
The full table on the hub →13 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 2 started in 2022.
Median enrollment 120 across the 6 interventional studies, 1,400 across the 7 observational. Of the 3 that completed or were terminated, 0 (0%) have results posted.
Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,592 studies on the registry; 1,033 are open to participants now.
1 of the studies in Myocarditis by Assistance Publique - Hôpitaux de Paris that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07077304Assistance Publique - Hôpitaux de ParisEACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases | 2027-08-31 |
Among the 13 studies in Myocarditis by Assistance Publique - Hôpitaux de Paris, from their registry updates:
Nothing recorded among them since 2026-09-25.
The AMPHIBIA study is an observational ambispective and prospective cohort that aim to describe the histologic, immunologic, biological, imaging, genetic and clinical characteristics of the patients hospitalized for an acute myocarditis and to evaluate their association with prognosis.
Acute myocarditis is an inflammatory disease of the heart muscle. Its clinical presentation and its etiologies are multiple and make it a complex disease to treat. Its course also varies, ranging from complete clinical recovery to recurrence of ventricular arrhythmia or progression to chronic dilated heart disease, while being difficult to predict. The long-term prognosis is poorly understood.
Consecutive patients hospitalized in a tertiary university referral center cohort from 2006 to 2041 for an acute myocarditis will be ambispectively or prospectively analyzed. This project will establish a registry including up to 400 patients in the ambispective analysis cohort from 2006 to 2021 and 1000 patients in the prospective analysis cohort during a 20 years inclusion period.
The aim of the study is to describe the characteristics of patients hospitalized for an acute myocarditis and to evaluate their association wih the long term (until 20 years) prognosis.
Features of interest will include :
The collection of clinical, biological and radiological data will represent an unique source allowing research teams in the coming years to access the data necessary to answer various specific questions (pathophysiological, diagnostic, prognostic) relevant to the state of knowledge on this pathology.
Patients hospitalised at Pitié-Salpêtrière hospital (Paris, France) for an acute myocarditis.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Biopsy and archival tissue
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients hospitalized for an acute myocarditis.
Major cardiac events
Defined as a composite of : * All cause death * Resuscitated cardiac arrest * Heart transplant * Longterm mechanical circulatory support * Ventricular arrhythmia after discharge * Hospitalization for heart failure * Hospitalization for myocarditis recurrence
Time frame: up to 1 years
Major cardiac events
Defined as a composite of : * All cause death * Resuscitated cardiac arrest * Heart transplant * Longterm mechanical circulatory support * Ventricular arrhythmia after discharge * Hospitalization for heart failure * Hospitalization for myocarditis recurrence
Time frame: up to 20 years
All cause death
Time frame: up to 20 years
Cardiovascular death
Time frame: up to 20 years
Heart transplant
Number of patients with heart transplant
Time frame: up to 20 years
Sustained ventricular arrhythmia after discharge
Number of patients with sustained ventricular arrhythmia after discharge
Time frame: up to 20 years
Resuscitated cardiac arrest
Number of patients with resuscitated cardiac arrest
Time frame: up to 20 years
Longterm mechanical circulatory support
Number of patients implanted with a longterm mechanical circulatory support
Time frame: up to 20 years
Hospitalization for myocarditis recurrence
Number of patients hospitalized for myocarditis recurrence
Time frame: up to 20 years
Hospitalization for heart failure
Number of patients with hospitalization for heart failure
Time frame: up to 20 years
Pericardial drainage
Number of patients with a surgery of pericardial drainage
Time frame: up to 20 years
Supra ventricular arrythmia
Number of patients with a new onset of supra ventricular arrhythmia
Time frame: up to 20 years
High grade atrioventricular block
Number of patients with a new high grade atrioventricular block
Time frame: up to 20 years
Pericarditis
Number of patients with pericarditis diagnosed by the patient referring physician's
Time frame: up to 20 years
Left ventricular systolic function under 50%
Evaluated by transthoracic echocardiography
Time frame: up to 20 years
Therapeutics during hospital stay
Type and duration of therapeutics received during the initial hospital stay
Time frame: From the day of admission up to 90 days
Plan to share: Undecided
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