An observational study in Endometriosis and Migraine, sponsored by Zurich University of Applied Sciences. Completed at 1 site in Switzerland. Open to female participants aged 18 Years to 99 Years. Per ClinicalTrials.gov, last updated 2022-02-24.
Sponsored by Zurich University of Applied Sciences · Observational
Patients with both, migraine and endometriosis, present the case-group, while women with endometriosis without migraine serve as controls. The primary endpoint is endometriosis stage confirmed by laparascopy compared to the control group. Further points to compare between groups are infertility, dysmenorrhea, dyschezia, dyspareunia, number of operations, family history with first-degree relatives, and age of first symptoms for both conditions and age at first operation.
Secondary endpoints to evaluate in percentages within the migraine group are migraine frequency, migraine aura/non-aura, age at migraine start, hormonal migraine, family history, treatment response, response to prophylactic agents, localization, types of aura and triggers. Other medical conditions and comorbidities like depression will be noted as well as response to Dienogest treatment.
In the questionnaire we will ask 62 Questions overall. The Questions for endometriosis are based on a questionnaire from the world endometriosis research foundation and to evaluate the severity of the migraine we will use the MIDAS (Migraine Disability Assessment) questionnaire (8).
1,528 studies on the registry are indexed under Migraine Disorders; 299 are open to participants now.
This study's enrollment of 344 is above the median of 130 across 299 observational studies indexed under Migraine Disorders.
Browse Migraine Disorders studies →Zurich University of Applied Sciences is the lead sponsor of 23 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
From our database of operated endometriosis patients ranging from 2016-2020 100 women will be identified within the first phone call as cases with endometriosis and migraine and the threefold number (n=300) as control with endometriosis only.
Exclusion Criteria:
* Premenopausal women aged 18-55 years, at time of operation * Endometriosis confirmed with surgery and histologic staging (Report of the surgery available) * For the cases migraine needs to be confirmed during the interview according to the IHS criteria.
Other: Questionaire
* Premenopausal women aged 18-55 years, at time of operation * Endometriosis confirmed with surgery and histologic staging (Report of the surgery available)
Other: Questionaire
only questionaire
Endometriosis stage
endometriosis stage confirmed by laparascopy compared to the control group
Time frame: 4 years
infertility, dysmenorrhea, dyschezia, dyspareunia, number of operations
s.o.
Time frame: 4 years
and age of first symptoms for both conditions and age at first operation
s.o.
Time frame: 4 years
family history with first-degree relatives,
s.o.
Time frame: 4 years
Secondary endpoints to evaluate in percentages within the migraine group are migraine frequency, migraine aura/non-aura, age at migraine start, hormonal migraine, family history, treatment response,
s.o.
Time frame: 4 years
response to prophylactic agents, localization, types of aura and triggers. Other medical conditions and comorbidities like depression will be noted
s.o.
Time frame: 4 years
Plan to share: No
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This study is completed, as verified in Feb 2022. You cannot join it, but the record below documents what was studied.
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Zurich University of Applied Sciences