An observational study in Sepsis and Children, Only, sponsored by Children's Hospital of Fudan University. Recruiting at 1 site in China. Open to participants aged 28 Days to 18 Years. Per ClinicalTrials.gov, last updated 2026-03-16.
Sponsored by Children's Hospital of Fudan University · Observational
The effect of continuous blood purification (CBP) in children is unclear. Also, the timing of early application is still being explored. In this study, we need to explore the efficacy and the timing of application of CBP in children with sepsis or septic shock.
Early intervention of CBP can remove inflammatory factors in patients with sepsis and reduce the damage of inflammatory factors to organs; at the same time, it can also promote the body's immune response, significantly improve immune dysfunction, and restore the body's immune balance. However, the timing of early application of CBP in childhood sepsis is still unclear. Therefore, it is necessary to further explore the treatment and prognosis of this technology in the early treatment of sepsis.
1,899 studies on the registry are indexed under Sepsis; 462 are open to participants now.
This study's planned enrollment of 90 is below the median of 160 across 931 observational studies indexed under Sepsis.
Browse Sepsis studies →Children's Hospital of Fudan University is the lead sponsor of 262 studies on the registry; 92 are open to participants now.
Counted across the registry records on this site, refreshed daily.
children with sepsis requiring blood purification to prevent or treat fluid overload or to clear cytokines
Exclusion Criteria:
The child with sepsis should be treated with CBP， but could not receive this treatment for various reasons
Procedure: CBP
The child with sepsis should be treated with CBP and received this treatment
continuous blood purification can prevent or treat fluid overload in children with septic shock or other sepsis-associated organ dysfunction who are unresponsive to fluid restriction and diuretic therapy management of septic AKI patients, particularly those with hemodynamic instability or fluid overload. Also, it can remove cytokines
Also known as: traditional therapy
survival rate
The survival rate of children in 28 days after hospital discharge
Time frame: 28 days after hospital discharge
The creatinine level of non-survival children with sepsis
The creatinine level of non-survival children with sepsis in 28 days after hospital discharge
Time frame: 28 days after hospital discharge
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Children's Hospital of Fudan University