A Phase 2 interventional study of Dentifrices in Plaque, Dental, sponsored by Church & Dwight Company, Inc.. Completed at 1 site in United States. Open to participants aged 18 Years to 69 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-03-12.
Sponsored by Church & Dwight Company, Inc. · Phase 2, Interventional, and Treatment
The purpose of this study is to evaluate and compare plaque removal efficacy of four dentifrices following a single timed tooth brushing. Prior to each evaluation visit of the four-way cross-over study, subjects will abstain from all oral hygiene for 24 hours. At each evaluation visit, subjects will be given a pre-brushing plaque evaluation, followed by a 1-minute supervised brushing and a post-brushing plaque evaluation.
This study is a randomized, single-brushing, examiner-blinded, 4-cell cross-over design that enrolled approximately 70 subjects to ensure that at least 60 subjects to complete the study. This 4-week cross-over study will evaluate plaque removal following a single brushing with the assigned dentifrices. Qualified subjects will have sufficient plaque (Lobene-Soparkar Modification of Turesky Plaque Index). Subjects will be given a pre-brushing plaque evaluation, followed by a 1-minute supervised brushing and a post-brushing plaque evaluation.
314 studies on the registry are indexed under Dental Plaque; 54 are open to participants now.
This study's enrollment of 70 is above the median of 59 across 279 interventional studies indexed under Dental Plaque.
Browse Dental Plaque studies →Church & Dwight Company, Inc. is the lead sponsor of 33 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Toothpaste with Stannous Fluoride
Drug: Dentifrices
Toothpaste with Sodium Fluoride and sodium bicarbonate
Drug: Dentifrices
Toothpaste with Stannous Fluoride
Drug: Dentifrices
Toothpaste with sodium Fluoride and sodium bicarbonate
Drug: Dentifrices
Dentifrice on plaque
Mean change from baseline (pre-brushing to post-brushing) in plaque score after single supervised use based on all surfaces of the whole mouth measured.
plaque evaluation
Time frame: up to 4 weeks
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2021. You cannot join it, but the record below documents what was studied.
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Church & Dwight Company, Inc.