An observational study in Viral Infection, Bacterial Infections and Lactate Blood Increase, sponsored by Daping Hospital and the Research Institute of Surgery of the Third Military Medical University. Completed at 1 site in China. Open to participants aged 1 Minute to 18 Years. Per ClinicalTrials.gov, last updated 2023-05-01.
Sponsored by Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Observational
Acute upper respiratory tract infection(AURI) is common in children, and viral infection is the main cause. However, several children with viral infection are easy to suffer from secondary bacterial infection, and the mechanism is unclear.
Lactate is an important molecule in the spread and metastasis of tumor by suppressing the innate immune response. As is known, the immune system is not mature in children and it is reverse related to the age of children. An reasonable hypothesis is that the lactate is a independent risk factor in the children with viral infection progress to bacterial infection. Here, our aim is to test the hypothesis.
656 studies on the registry are indexed under Virus Diseases; 85 are open to participants now.
This study's enrollment of 400 is close to the median of 442 across 167 observational studies indexed under Virus Diseases.
Browse Virus Diseases studies →Daping Hospital and the Research Institute of Surgery of the Third Military Medical University is the lead sponsor of 121 studies on the registry; 42 are open to participants now.
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The age of a child ranged from 0 to 18 is included in the present study, especially the first viral infection.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
one of the following conditions appeared:
a child is infected by virus only
Other: viral infection
a child is infected by virus and progress to bacterial infection
Other: viral and bacterial infection
a child is infected by virus only
a child is infected by virus and progress to bacterial infection
level of lactate
level of lactate in both viral and viral and bacterial infection groups
Time frame: three days after admission
the level of lactate dehydrogenase(LDH)
level of LDH in both viral and viral and bacterial infection groups
Time frame: three days after admission
Plan to share: Yes — two years after the study accomplishment
Supporting information: Study protocol, Statistical analysis plan, Clinical study report
Time frame: from Jan-1, 2025 to Dec-31, 2025
No publications or documents are linked to this record.
This study is completed, as verified in Oct 2022. You cannot join it, but the record below documents what was studied.
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Daping Hospital and the Research Institute of Surgery of the Third Military Medical University →