An observational study in COVID 19, sponsored by Ankara University. Recruiting at 1 site in Turkey. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-12-15.
Sponsored by Ankara University · Observational
COVID-19 (Coronavirus disease 2019) is a new infectious disease caused by a virus named as SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2). Although it can have a devastating effect on many organs, the respiratory tract is particularly affected. In the course of the disease, a wide clinical spectrum is observed, from flu-like illness to lung failure. Some of the patients who survived the disease continue to have problems such as shortness of breath, fatigue, decrease in walking distance, decrease in participation in daily life activities. These problems suggest that the effects on respiratory and cardiac functions continue even after the disease ends. This study was designed to demonstrate the effects and extent of COVID-19 on cardiopulmonary capacity.
Aims of the research are that demonstrate change in cardiopulmonary fitness level in patients with COVID-19 according to normal values and reveal the relationship of this change with age, gender, physical activity level, disease severity and accompanying medical conditions.
Patients older than 18 years old who are diagnosed with COVID-19 according to clinical symptoms and rt-PCR test positivity and at least 30 days past the end of their symptoms are accepted for the study.
According to World Health Organization's (WHO) classification, COVID-19 disease severity is determined. Physical activity level of the patients before COVID-19 is evaluated with International Physical Activity Questionnaire. Risk of anxiety and depression of the patients is identified with Hospital Anxiety and Depression Scale (HADS), which has 14 questions. To evaluate cardiopulmonary fitness level, cardiopulmonary exercise test (CPET) and 6-minute walk test are applied. Cardiopulmonary exercise test is gold standard to determine cardiac and respiratory functions. Pulmonary function test is performed to identify the conditions that affect the results of cardiopulmonary exercise test.
7,641 studies on the registry are indexed under COVID-19; 487 are open to participants now.
This study's planned enrollment of 240 is close to the median of 261 across 3,136 observational studies indexed under COVID-19.
Browse COVID-19 studies →Ankara University is the lead sponsor of 312 studies on the registry; 68 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients applying to COVID-19 follow-up clinics
Exclusion Criteria:
Symptomatic patients meeting the case definition for COVID-19 without evidence of viral pneumonia or hypoxia.
Other: Physical Activity Level · Other: Anxiety and Depression Assessment · Diagnostic Test: Exercise Capacity · Diagnostic Test: Pulmonary Function Test · Diagnostic Test: Cardiopulmonary Fitness Level · Other: Cognitive Assessment
Patients with clinical signs of pneumonia (fever, cough, dyspnoea, fast breathing) but no signs of severe pneumonia, including SpO2 ≥ 90% on room air
Other: Physical Activity Level · Other: Anxiety and Depression Assessment · Diagnostic Test: Exercise Capacity · Diagnostic Test: Pulmonary Function Test · Diagnostic Test: Cardiopulmonary Fitness Level · Other: Cognitive Assessment
Patients with clinical signs of pneumonia (fever, cough, dyspnoea,fast breathing) plus one of the following: respiratory rate \> 30 breaths/min; severe respiratory distress; or SpO2 \< 90% on room air.
Other: Physical Activity Level · Other: Anxiety and Depression Assessment · Diagnostic Test: Exercise Capacity · Diagnostic Test: Pulmonary Function Test · Diagnostic Test: Cardiopulmonary Fitness Level · Other: Cognitive Assessment
Patients have one of the following: acute respiratory distress syndrome; sepsis; or septic shock.
Other: Physical Activity Level · Other: Anxiety and Depression Assessment · Diagnostic Test: Exercise Capacity · Diagnostic Test: Pulmonary Function Test · Diagnostic Test: Cardiopulmonary Fitness Level · Other: Cognitive Assessment
International Physical Activity Questionnaire
Hospital Anxiety and Depression Scale
6 Minute Walk Test
Spirometry
Cardiopulmonary Exercise Test
Montreal Cognitive Assessment
Peak oxygen uptake
Cardiopulmonary exercise test
Time frame: 1-6 months
Oxygen uptake at anaerobic threshold
Cardiopulmonary exercise test
Time frame: 1-6 months
Borg rating of perceived exertion scale
Cardiopulmonary exercise test
Time frame: 1-6 months
Walk distance
6 minute walk test
Time frame: 1-6 months
Borg dyspnea scale
Cardiopulmonary exercise test
Time frame: 1-6 months
Anxiety score
Hospital Anxiety and Depression Scale
Time frame: 1-6 months
Depression score
Hospital Anxiety and Depression Scale
Time frame: 1-6 months
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Ankara University