CClinicalTrials.gg
Status unknownNCT04741217Updated Feb 15, 2021

Aerosolisation During Respiratory Procedures

An observational study in Healthy, Respiratory Tract Infections and Lung Infection, sponsored by Guy's and St Thomas' NHS Foundation Trust. Status unknown. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2021-02-15.

Sponsored by Guy's and St Thomas' NHS Foundation Trust · Observational

The sponsor has not verified this record recently (last verified Aug 2020), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
10
Ages
18 Years to 80 Years
Sex
All
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Study summary

Currently, a major issue within respiratory medicine is undertaking procedures that generate aerosolisation with the concern of spreading infection, such as the SARS-COV-2/COVID-19 virus. It is anecdotally reported that lung function testing and positive airways pressure devices used in clinical practice are aerosol generating procedures however the data to support this is limited. With the advent of high-speed imaging systems that can capture and quantify particle size and velocity we aim to investigate the aerosol generation in routine non-invasive positive pressure respiratory procedures.

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Conditions studied

  • Healthy
  • Respiratory Tract Infections
  • Lung Infection
  • Droplet Spread
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In context

Infections

6,687 studies on the registry are indexed under Infections; 807 are open to participants now.

This study's planned enrollment of 10 is below the median of 240 across 2,136 observational studies indexed under Infections.

Browse Infections studies →

Lead sponsor

Guy's and St Thomas' NHS Foundation Trust is the lead sponsor of 284 studies on the registry; 79 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Healthy subjects

Inclusion criteria

  • Age 18-80 years
  • Healthy subjects with no active medical conditions or previous pneumothorax
  • Cognitively and linguistically able to follow instructions given in English and provide informed consent

Exclusion criteria

Exclusion Criteria:

  • Significant respiratory, cardiac or neurological conditions or previous pneumothorax
  • Smoking history greater than 10 pack years
  • Acute illness at the time of assessment
  • Allergies to latex, metals or local anaesthetic agents
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
10 participants (estimated)
Patient registry
No

Interventions

  • OtherNot an interventional study

    No interventions are implemented. This is an observational study of respiratory droplet aerosolisation during respiratory procedures.

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What researchers measure

Primary outcomes

  1. Characterisation of aerosolised respiratory droplets

    Performed using high-speed imaging and particle size counters

    Time frame: 1 year

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: Undecided — Anonymised data may be shared based upon consideration of reasonable requests from researchers with a stated objective.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 15, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04741217
Lead sponsor
Guy's and St Thomas' NHS Foundation Trust
Responsible party
Sponsor
First posted
Feb 5, 2021
Start date
Mar 1, 2021 (estimated)
Primary completion
Sep 1, 2021 (estimated)
Completion
Sep 1, 2021 (estimated)
Last update
Feb 15, 2021

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Aug 2020. You cannot join it, but the record below documents what was studied.

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Discussion

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