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CompletedNCT04709588Updated Jan 14, 2021

Hydrolyzed Collagen Combined With Djulis and Green Caviar Improve Skin Condition

An interventional study of placebo group and collagen drinkss in Skin Condition, sponsored by TCI Co., Ltd.. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-01-14.

Sponsored by TCI Co., Ltd. · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 8 months after the study started (first participant enrolled May 2020, registered Jan 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
20 Years to 65 Years
Sex
All
01

Study summary

Collagen combined with djulis and green caviar improve skin condition

Read the detailed description

Using collagen drinks combined fish collagen with djulis, and green caviar to improve skin condition.

02

Conditions studied

  • Skin Condition
03

In context

Skin Diseases

538 studies on the registry are indexed under Skin Diseases; 92 are open to participants now.

This study's enrollment of 50 is below the median of 60 across 372 interventional studies indexed under Skin Diseases.

Browse Skin Diseases studies →

Lead sponsor

TCI Co., Ltd. is the lead sponsor of 60 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. Dry skin
  2. Rough skin
  3. Large pores
  4. Dark yellow complexion
  5. Sagging skin

Exclusion criteria

Exclusion Criteria:

  1. Skin disorders
  2. Liver diseases
  3. Kidney diseases
  4. Allergy to cosmetics, drugs, or foods
  5. Pregnant and lactating women
  6. People who had any cosmetic procedures before 4 weeks of the study
  7. Area of facial spot over 3 cm2
  8. Vegan
  9. People who took collagen supplements in the past 3 months.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
50 participants (actual)

Study arms

  • Placebo comparator
    placebo group

    subjects drank 50 ml every night for 14, 28 days

    Dietary Supplement: placebo group

  • Experimental
    collagen drinks

    subjects drank 50 ml every night for 14, 28 days

    Dietary Supplement: collagen drinkss

Interventions

  • Dietary supplementplacebo group

    subjects drank 50 ml every night for 14, 28 days

  • Dietary supplementcollagen drinkss

    subjects drank 50 ml every night for 14, 28 days

06

What researchers measure

Primary outcomes

  1. skin moisture

    using corneometer CM825 to examine skin moisture (The higher the value, the more water content, C.U., corneometer units )

    Time frame: subjects drank 50 ml every night for 28 days

  2. skin elasticity

    using cutometer dual MPA580 to examine skin elasticity (The closer the R2 value is to 1, the better the elasticity and no unit)

    Time frame: subjects drank 50 ml every night for 28 days

  3. skin gloss

    using probe system GL2000 \& MPA10 to examine skin gloss (The higher the value, the higher the gloss, no unit)

    Time frame: subjects drank 50 ml every night for 28 days

  4. skin spot

    usig VISIA-CR to examine skin spot (The higher the value, the larger the pore area, mm2)

    Time frame: subjects drank 50 ml every night for 28 days

  5. skin wrinkle

    using VISIOSCAN-VC20 to examine skin wrinkle (The higher the value, the more wrinkles, surface evaluation of wrinkles, SEW)

    Time frame: subjects drank 50 ml every night for 28 days

  6. skin roughness

    using VISIOSCAN-VC98 to examine skin roughness (The higher the value, the higher the roughness, surface evaluation of roughness, SEr)

    Time frame: subjects drank 50 ml every night for 28 days

  7. skin smoothness

    using VISIOSCAN-VC98 to examine skin smoothness (The lower the value, the higher the smoothness, surface evaluation of smoothness, SEsm)

    Time frame: subjects drank 50 ml every night for 28 days

07

Study locations

1 site
  • Research & Design Center, TCI CO., Ltd
    Taipei, Taiwan
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 14, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04709588
Lead sponsor
TCI Co., Ltd.
Responsible party
Sponsor
First posted
Jan 14, 2021
Start date
May 1, 2020
Primary completion
Jun 30, 2020
Completion
Aug 31, 2020
Last update
Jan 14, 2021

Study contacts

Chi Fu Chiang, Ph.D
principal investigator · Research & Design Center, TCI CO., Ltd

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.

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