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CompletedNCT04681898Endo-MetriosUpdated Jan 31, 2022

Incidence of Different Surgical Technics for Colorectal Deep Infiltrating EndoMetriosis on the Post-operative Fertility and Pregnancy Outcomes

An observational study in Endometriosis, sponsored by University Hospital, Strasbourg, France. Completed at 1 site in France. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-01-31.

Sponsored by University Hospital, Strasbourg, France · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
164
Ages
18 Years and older
Sex
Female
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Study summary

Endometriosis is a disease that is very present on the current media scene. Its symptoms are very nonspecific and numerous. (dysmenorrhea, dyspareunia, dyschezia, urinary functional signs, infertility, chronic pelvic pain, etc.) Its prevalence is estimated at 10% of women and 20% of them have deep pelvic endometriosis. Colorectal lesions involving the rectosigmoid junction and the rectum represent the most severe forms and affect 5.3 to 12% of patients with deep pelvic endometriosis. Endometriosis is found in 20 to 50% of patients consulting for infertility and the rate of spontaneous pregnancy in patients with deep endometriosis is estimated to be between 8.7 and 13%. Surgery appears to improve fertility in women. However, several surgical techniques for deep endometriosis at the digestive level have been described, conservative or radical, without any having demonstrated its superiority both in terms of symptoms and fertility.

The aim of this study was to evaluate the incidence of different surgical technics (shaving vs. bowel resection) on post-operative fertility among patients with bowel deep infiltrating endometriosis and the pregnancy outcome

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Conditions studied

  • Endometriosis

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Keywords

  • colorectal endometriosis
  • deep infiltrating endometriosis
  • fertility
  • surgical technics in endometriosis
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In context

Endometriosis

901 studies on the registry are indexed under Endometriosis; 259 are open to participants now.

This study's enrollment of 164 is above the median of 128 across 344 observational studies indexed under Endometriosis.

Browse Endometriosis studies →

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 966 studies on the registry; 342 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult woman with a desire to become pregnant and who had undergone surgery for the management of deep digestive endometriosis between September 01, 2009 and October 31, 2016.

Inclusion criteria

  • Adult woman (≥18 years old).
  • woman with a desire to become pregnant and who had undergone surgery for the management of deep digestive endometriosis between September 01, 2009 and October 31, 2016.
  • Woman who has not expressed, after information, the reuse of her data for the purposes of this research.

Exclusion criteria

Exclusion Criteria:

  • Woman who expressed her opposition to participating in the study
  • Woman who had undergone a surgical intervention for the management of deep digestive endometriosis between September 01, 2009 and October 31, 2016 and having no desire to become pregnant
  • Woman under safeguard of justice
  • Woman under guardianship or guardianship
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Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
164 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Retrospective analysis of the rate of occurrence of pregnancy postoperatively.

    Time frame: Files analysed retrospectily from September 1st, 2009 to October 31, 2016 will be examined

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Study locations

1 site
  • Department of Gynecology - Strasbourg University Hospitals
    Strasbourg, 67091, France
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 31, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04681898
Lead sponsor
University Hospital, Strasbourg, France
Responsible party
Sponsor
First posted
Dec 23, 2020
Start date
Dec 30, 2020
Primary completion
Nov 30, 2021
Completion
Dec 31, 2021
Last update
Jan 31, 2022

Study contacts

Émilie FALLER
study director · Department of Gynecology - Strasbourg University Hospitals

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.

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