An interventional study of Placebo and Babyguard® Breast Milk Probiotics in Intestinal Bacteria Flora Disturbance, sponsored by TCI Co., Ltd.. Completed at 1 site in Taiwan. Open to female participants aged 20 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-10.
Sponsored by TCI Co., Ltd. · Not applicable, Interventional, and Treatment
In order to understand the life history of the breast milk flora, explore its composition, source of strains, and ability to colonize the baby's intestinal environment, to find out strains with the potential of probiotics in breast milk
This is a double-blind and randomized study. After being discharged from the hospital, the subject was notified to consume the Babyguard breast milk probiotic daily for 1 month, and observe whether the mother's stool, breast milk and baby stool samples can find the same strain. The clinical diagnosis items of the bacterial strains of mother feces, breast milk and baby feces samples are evaluated by the doctor.
186 studies on the registry are indexed under Dysbiosis; 59 are open to participants now.
This study's enrollment of 30 is below the median of 60 across 134 interventional studies indexed under Dysbiosis.
Browse Dysbiosis studies →TCI Co., Ltd. is the lead sponsor of 60 studies on the registry; 7 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
consume 1 sachet per day for 1 months
Dietary Supplement: Placebo
consume 1 sachet per day for 1 months
Dietary Supplement: Babyguard® Breast Milk Probiotics
consume 1 sachet per day for 1 months
consume 1 sachet per day for 1 months
Microflora of mother's feces
Collect mother's feces for bacterial analysis.The mother's feces use Qiagen stool mini kit to extract DNA, and then use the intestinal bacteria primers to detect the presence of intestinal bacteria in the feces.
Time frame: 4-6 weeks after the baby is born
Group. B Streptococcus (GBS) screening
Use sterile cotton sticks for vaginal samples, and then perform Group. B Streptococcus (GBS) screening
Time frame: 35-37 weeks of pregnancy
The microflora of maternal blood
Use venous blood to collect 20 ml of mother's blood for bacterial analysis.The mother's blood uses Qiagen DNA isolation mini kit to extract DNA, and then uses intestinal bacteria primers to detect the presence of intestinal bacteria in the blood
Time frame: 4-6 weeks after the baby is born
Metabolic analysis of maternal urine
Collect 10 ml of mother's urine for intestinal dysbiosis analysis. Use Qiagen DNA isolation mini kit to extract DNA from the mother's urine, and then use the intestinal bacteria primer to detect the presence of intestinal bacteria in the urine.
Time frame: 4-6 weeks after the baby is born
Bacteria analysis of breast milk
Collect 10 ml of breast milk for bacterial phase analysis.Use Qiagen DNA isolation mini kit to extract DNA from breast milk, and then use intestinal bacteria primers to detect whether the breast milk contains intestinal bacteria.
Time frame: 4-6 weeks after the baby is born
Bacteria analysis of infant feces
Collect baby feces for bacterial phase analysis.Use Baby feces use Qiagen stool mini kit to extract DNA, and then use intestinal bacteria primers to detect the presence of intestinal bacteria in the feces.
Time frame: 4-6 weeks after the baby is born
This study is completed, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
TCI Co., Ltd.