An interventional study of Device programming in Heart Failure, sponsored by Medical University Innsbruck. Recruiting at 1 site in Austria. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-10-02.
Sponsored by Medical University Innsbruck · Not applicable, Interventional, and Diagnostic
The principal aim is to analyze total left and right ventricular activation time in different CRT device programming algorithms (SyncAV) measured by non-invasive electrophysiology
Patient specific anatomic parameters taken from the cardiac magnetic resonance examination will be the base for a semiautomatic model incorporating the conductivity of the heart, the lungs, blood and the torso. For this reason, a software package (AMIRA Developer, TGS Template Graphics Software, France) has been adapted to calculate a quasi static approximation of Maxwell equations.
After fusion of the T1 CMR scan and the ECG electrodes a model-based bidomain FEM is used for a step-wise measurement of the local activation times (resting potential: 290 mV; plateau: 0 mV; acceleration time: 3 ms) both Ende- and epicardially.
5,701 studies on the registry are indexed under Heart Failure; 1,220 are open to participants now.
This study's planned enrollment of 25 is below the median of 72 across 3,736 interventional studies indexed under Heart Failure.
Browse Heart Failure studies →Medical University Innsbruck is the lead sponsor of 182 studies on the registry; 49 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
according to different settings from the SyncAV algorithm
Device: Device programming
Non-invasive electrophysiology with 65 ECG leads will be performed in 16 different device programming
Optimal (shortest) activation time of the right and left ventricular in heart failure patients after CRT implantation
The activation time will be measured in 16 different device programming settings
Time frame: The measurements will be done at Day 1
Plan to share: No
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Medical University Innsbruck