An observational study in Breast Cancer, sponsored by City of Hope Medical Center. Active, not recruiting at 1 site in United States. Per ClinicalTrials.gov, last updated 2025-12-05.
Sponsored by City of Hope Medical Center · Observational
This trial studies long term follow-up care in patients with stage 0-IIIC breast cancer. Collecting feedback from breast cancer patients may help researchers to define comprehensive long term follow-up care for breast cancer survivors, better understand health-related quality of life and long-term complications in breast cancer survivors, and to increase the knowledge of the mechanisms by which a patient's own immune system attempts to combat breast cancer, and what factors may make this response more successful.
PRIMARY OBJECTIVES:
I. To provide comprehensive care to breast cancer survivors diagnosed with stage 0 to IIIC, who received at least part of their treatment at City of Hope.
II. To use the information obtained from follow-up of breast cancer survivors to describe the magnitude of risk and associated risk factors.
III. To use the information gained from follow-up of breast cancer survivors to describe health-related quality of life (HRQL) concerns in breast cancer survivors and identify those at highest risk.
OUTLINE:
Patients undergo long term follow-up and complete questionnaires.
12,544 studies on the registry are indexed under Breast Neoplasms; 2,892 are open to participants now.
This study's planned enrollment of 500 is above the median of 184 across 2,642 observational studies indexed under Breast Neoplasms.
Browse Breast Neoplasms studies →City of Hope Medical Center is the lead sponsor of 670 studies on the registry; 181 are open to participants now.
Of its 30 completed or terminated interventional studies of FDA-regulated products, 12 (40%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients with stage 0-IIIC breast cancer
Exclusion Criteria:
Patients undergo long term follow-up and complete questionnaires.
Other: Long-term Follow-up · Other: Questionnaire Administration · Other: Quality-of-Life Assessment
Undergo long term follow-up
Also known as: LONG-TERM FOLLOW-UP, Long-term Follow-up
Ancillary studies
Ancillary studies
Also known as: Quality of Life Assessment
Incidence rates of the study end-points
Will estimation of incidence rates of the study end-points that may be associated with original diagnosis or treatment received, and delineation of temporal changes in serial measurements and their relationship to time-invariant characteristics such as original diagnosis, race, and education and time varying characteristics such as age and body mass index (BMI). Incidence rates may be compared with national standards adjusted for key demographic variables and between patient subgroups. Time of entry onto the study in the analysis will be from the date of diagnosis of primary disease. Stepwise logistic regression analysis of endpoints of interest at certain follow-up time may be conducted, accounting for the joint effect of such factors as age, time since diagnosis and treatment, radiation dose, chemotherapy and tumor subtype.
Time frame: Up to 12 years
FACT- Cog
Functional Assessment of Cancer Therapy Cognitive Function
Time frame: Change from pre-treatment baseline over a 2-year period
Cancer induced immune dysfunction
Will analyze patients' tumor, lymph node, and blood samples
Time frame: Up to 12 years
This study is active, not recruiting, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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City of Hope Medical Center