An interventional study of Best Practice and Educational Intervention in Hematopoietic and Lymphoid Cell Neoplasm and Malignant Solid Neoplasm, sponsored by Mayo Clinic. Terminated at 3 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-04.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Health services research
This clinical trial investigates the challenges, behavioral patterns, and preferences towards participation in clinical trials in minority patient populations in order to develop a personalized clinical trial educational platform to increase participation in clinical trials among underserved cancer patients. Learning more about patients' understanding of clinical trials may help identify barriers that limit patient's participation. Information gathered from this trial will be used to develop educational materials that may aid minority patients in overcoming barriers to participating in clinical trials. A personalized clinical trial educational platform may help increase participation in clinical trials among minority populations.
PRIMARY OBJECTIVES:
I. To understand and document patient preferences, understanding, and attitudes regarding clinical trials.
II. To compare patient attitudes regarding clinical trials among cancer patients belonging to different racial/ethnic groups.
III. To establish the magnitude of existing knowledge gap relating to clinical trials among underserved cancer patients and the extent of improvement with a personalized educational approach.
IV. To determine how a personalized educational approach impacts enrollment in clinical trials of underserved cancer patients.
OUTLINE:
PART I: Patients complete a questionnaire about their preferences, understanding, and attitudes regarding clinical trials. Patients also have their medical records reviewed.
PART II: Patients are randomized to 1 of 2 arms.
ARM A: Patients undergo clinical trial education via a video and educational booklet and then standard of care follow-up on study.
ARM B: Patients undergo clinical trial education via a video and educational booklet and then undergo patient navigation with active clinical trial matching and receive clinical trial information through the electronic medical record portal on study.
1,464 studies on the registry are indexed under Hematologic Neoplasms; 433 are open to participants now.
This study's enrollment of 590 is above the median of 45 across 1,068 interventional studies indexed under Hematologic Neoplasms.
Browse Hematologic Neoplasms studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients complete a questionnaire about their preferences, understanding, and attitudes regarding clinical trials. Patients also have their medical records reviewed.
Other: Electronic Health Record Review · Other: Questionnaire Administration
Patients undergo clinical trial education via a video and educational booklet and then standard of care follow-up on study.
Other: Best Practice · Other: Educational Intervention · Other: Electronic Health Record Review · Other: Questionnaire Administration
Patients undergo clinical trial education via a video and educational booklet and then undergo patient navigation with active clinical trial matching and receive clinical trial information through the electronic medical record portal on study.
Other: Best Practice · Other: Educational Intervention · Other: Electronic Health Record Review · Behavioral: Patient Navigation · Other: Questionnaire Administration
Undergo standard of care follow-up
Also known as: standard of care, standard therapy
Undergo clinical trial education via a video and educational booklet
Also known as: Education for Intervention, Intervention by Education, Intervention through Education, Intervention, Educational
Review of medical record
Undergo clinical trial navigation
Also known as: Patient Navigator Program
Complete questionnaire
Documentation of patient preferences, understanding, and attitudes regarding clinical trials (part I)
Overall percentages of the individual categories for each item of the survey will be summarized across all individuals. Any continuous items collected will be summarized using Means and/or medians depending on the distribution of the data. Most of this analysis will be exploratory and viewed as hypothesis generating.
Time frame: Baseline
Comparison of patient attitudes regarding clinical trials among cancer patients belonging to different racial/ethnic groups (part I)
Overall percentages of the individual categories for each item of the survey will be summarized across all individuals. Most of this analysis will be exploratory and viewed as hypothesis generating.
Time frame: Baseline
Knowledge score (part II)
Knowledge score at baseline in underserved groups will be compared with knowledge score of non-underserved cancer patients in the study.
Time frame: Baseline
Change in knowledge score (part II)
Knowledge score at baseline will be compared with scores at 6 months and 12 months. Scores of patients enrolled in the educational intervention and in the comparator arm will be reviewed.
Time frame: Baseline up to 6 and 12 months
Patient enrollment in a clinical trial
The binary outcome of whether or not each patient is enrolled in a trial or not, focusing on the underserved patients. The proportion of patients enrolled in a trial will be compared in each of the two study arms.
Time frame: Up to 24 months
This study is terminated, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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