An observational study in Deep Vein Thrombosis, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-01-31.
Sponsored by Mayo Clinic · Observational
The goal of this study is to examine in vivo thrombosis characteristics with ultrasound shear wave elastography (SWE) and determine the relationship with thrombus resolution and postthrombotic syndrome (PTS) in patients with acute proximal Deep Vein Thrombosis (DVT).
1,508 studies on the registry are indexed under Thrombosis; 239 are open to participants now.
This study's enrollment of 35 is below the median of 213 across 588 observational studies indexed under Thrombosis.
Browse Thrombosis studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients with acute, proximal DVT initiating anticoagulation
Exclusion Criteria
Thrombus Resolution
Ultrasound images of lower extremity DVTs comparing the initial diagnostic image of thrombus to a subsequent study performed after 3 months of anticoagulation.The lower extremity venous system is divided into 12 segments. Each vein segment will be analyzed on initial ultrasound and recorded 0 (no DVT), 1 (non-occlusive DVT), or 2 (occlusive DVT). The follow up ultrasound will be analyzed per vein segment and recorded as no residual thrombus, minimal chronic post-thrombotic changes, \> 50% resolution, \< 50% resolution, near occlusive DVT, no change, and progressive DVT.
Time frame: 3 Months after diagnosis of DVT.
Post-thrombotic syndrome
Measured using the Villalta Score. Scale 0-33 with higher values indicating more severe symptoms.
Time frame: 6 months after diagnosis of DVT
Vein Specific Quality of Life
Measured using The Venous Insufficiency Epidemiological and Economic Study (VEINES) QOL survey. Scores range from 0-100 with higher scores indicating better quality of life.
Time frame: 6 months after diagnosis of DVT
Post-thrombotic syndrome
Measured using the Villalta Score. Scale 0-33 with higher values indicating more severe symptoms.
Time frame: 3 and 12 months after diagnosis of DVT
Vein Specific Quality of Life
Measured using The Venous Insufficiency Epidemiological and Economic Study (VEINES) QOL survey. Scores range from 0-100 with higher scores indicating better quality of life.
Time frame: 3 and 12 months after diagnosis of DVT
Thrombus Resolution
Measured quantitatively by outflow parameters on air plethysmography with expelled volume measured at 1 second x 60 sec (ml/100ml/minute), expelled volume after 4 seconds, and maximum volume expelled.
Time frame: 3 Months after diagnosis of DVT.
This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Mayo Clinic