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CompletedNCT04557644Updated Nov 4, 2021

Contagious Itch, Disgust and Empathy in Patients and Medical Staff

An interventional study of 7-items-questionnaires addressing CI, disgust and empathy and Saarbrucken Personality questionnaire (SPQ) addressing empathy. in Contagious Itch, sponsored by University Hospital, Basel, Switzerland. Completed at 1 site in Switzerland. Open to participants aged 7 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-11-04.

Sponsored by University Hospital, Basel, Switzerland · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
24
Allocation
Non-randomized
Ages
7 Years and older
Sex
All
01

Study summary

This study is to assess the relationship between CI, disgust and empathy in medical staff treating patients with scabies, to differentiate the impact of visual and verbal stimuli contributing to CI and to assess information about CI, disgust and empathy in a family infested with scabies.

Read the detailed description

Itch is the commonest skin-related symptom, defined as a bodily sensation provoking the urge to scratch. The induction of itch and scratching by mere (audio-) visual stimuli such as pictures of insects on skin or video clips showing individuals scratching themselves, indicates that itch can be perceived in the absence of a pruritogenic somatosensory stimulus. This phenomenon is referred to as "contagious itch" (CI). CI may play a special role in the content of scabies both for the affected patients as well as the treating staff: It is a very common phenomenon that family members who are not infested by scabies themselves experience itch when watching their infested relatives scratching. The same is very frequently expressed by health care professionals being confronted with scabies patients. Two further important factors may be involved in the context of CI: disgust and empathy. Empathy is defined as a psychological concept that enables individuals to understand and share emotions of others. Disgust is an emotional response of revulsion to potentially contagious and/or harmful objects or subjects. This study is to assess the relationship between CI, disgust and empathy in medical staff treating patients with scabies, to differentiate the impact of visual and verbal stimuli contributing to CI and to assess information about CI, disgust and empathy in a family infested with scabies.

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Conditions studied

  • Contagious Itch

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Keywords

  • itch
  • scabies
  • ectoparasites
  • post-scabetic itch
  • disgust
  • empathy
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In context

Pruritus

354 studies on the registry are indexed under Pruritus; 74 are open to participants now.

This study's enrollment of 24 is below the median of 60 across 294 interventional studies indexed under Pruritus.

Browse Pruritus studies →

Lead sponsor

University Hospital, Basel, Switzerland is the lead sponsor of 968 studies on the registry; 191 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
7 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • members of families (aged >7 years) hospitalized in the Department of Dermatology with scabies
  • staff (physicians, nurses, nurse aids aged >16 years) involved in the treatment of these families
  • Infestation of scabies in individual family members confirmed by two leading dermatologists of the University Hospital Basel by dermoscopy and/or skin scrapings.

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
24 participants (actual)

Study arms

  • Active comparator
    medical staff treating patients with scabies

    Other: 7-items-questionnaires addressing CI, disgust and empathy · Other: Saarbrucken Personality questionnaire (SPQ) addressing empathy.

  • Active comparator
    family infested with scabies

    Other: Saarbrucken Personality questionnaire (SPQ) addressing empathy. · Other: 10-items-questionnaire addressing previous dermatological conditions, intensity of itch · Other: ItchyQol-questionnaire composed of 22 items addressing itch-related symptoms, functions and emotions

Interventions

  • Other7-items-questionnaires addressing CI, disgust and empathy

    7-items-questionnaire including numerical rating scales (NRS) ranging from 0 (no itch/disgust/empathy) to 10 (worst itch/disgust/most empathy imaginable) to rate itch, disgust and empathy they experience when treating the infested families.

  • OtherSaarbrucken Personality questionnaire (SPQ) addressing empathy.

    Empathy is additionally assessed by the Saarbrucken Personality Questionnaire (SPQ) ,a 16-item tool.

  • Other10-items-questionnaire addressing previous dermatological conditions, intensity of itch

    10-items-questionnaire (completed by the hospitalised family) regarding demographic information (gender, age, profession), previous dermatological conditions, intensity of itch a.) on the first day of the hospitalisation, b.) when seeing the skin lesions of the other family members c.) when talking about the scabies/itch with the other family members, d.) when seeing other family members scratching themselves, and questions regarding their intensity of disgust of the scabies and empathy for the other family members (0-10 NRS).

  • OtherItchyQol-questionnaire composed of 22 items addressing itch-related symptoms, functions and emotions

    ItchyQol-questionnaire to assess the itch-related quality of life impairment. The ItchyQoL is composed of 22 items addressing itch-related symptoms, functions and emotions.

06

What researchers measure

Primary outcomes

  1. Intensity of emotion (CI, disgust and empathy) in medical staff treating patients with scabies

    Score in 7-items-questionnaire including numerical rating scales (NRS) ranging from 0 (no itch/disgust/empathy) to 10 (worst itch/disgust/most empathy imaginable) to rate itch, disgust and empathy they experience when treating the infested families. The questionnaire (see Appendix) contains questions regarding demographic information (gender, age, profession), previous dermatological conditions, intensity of itch a.) before interacting with the patients, b.) when listening to the patients telling about their infestation with scabies, c.) when seeing the skin lesions, d.) when seeing patients scratching themselves, and questions regarding their intensity of disgust of the scabies and empathy for the families (0-10 NRS).

    Time frame: one point assessment at baseline

  2. Intensity of emotion (CI, disgust and empathy) in family infested with scabies

    Score in 10-items-questionnaire addressing intensity of itch a.) on the first day of their hospitalisation, b.) when seeing the skin lesions of the other family members c.) when talking about the scabies/itch with the other family members, d.) when seeing other family members scratching themselves and intensity of disgust of the scabies and intensity of empathy for the other family members (0-10 NRS).

    Time frame: one point assessment at baseline (first day of hospitalisation)

  3. Empathy scored by Saarbrucken Personality Questionnaire (SPQ)

    The Saarbrucken personality questionnaire SPQ is the German version of the Interpersonality Reactivity Index (IRI) used for the measurement of empathy. The tool is a self-report answered on a 5-point Likert scale ranging from "Does not describe me well" to "Describes me very well".

    Time frame: one point assessment at baseline (first day of hospitalisation)

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Study locations

1 site
  • Department of Dermatology; University Hospital Basel
    Basel, 4031, Switzerland
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 4, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04557644
Lead sponsor
University Hospital, Basel, Switzerland
Responsible party
Sponsor
First posted
Sep 21, 2020
Start date
Sep 16, 2020
Primary completion
Oct 31, 2021
Completion
Oct 31, 2021
Last update
Nov 4, 2021

Study contacts

Simon Mueller, PD Dr. med.
principal investigator · Department of Dermatology, University Hospital Basel

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Nov 2021. You cannot join it, but the record below documents what was studied.

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