An interventional study of V01 candy and V02 candy in Xerostomia and Dryness of Mouth, sponsored by University Hospital, Basel, Switzerland. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-02-21.
Sponsored by University Hospital, Basel, Switzerland · Not applicable, Interventional, and Treatment
This study is to investigate whether a candy can increase moisture of the oral cavity and reduce dryness of mouth.
A candy (available on the market from a Swiss manufacturer (Ricola)), free of ingredients that could interfere with the investigation, is tested in five different versions on different days. It is to analyse whether these candies can increase moisture of the oral cavity and reduce dryness of mouth.
264 studies on the registry are indexed under Xerostomia; 48 are open to participants now.
This study's enrollment of 33 is below the median of 42 across 223 interventional studies indexed under Xerostomia.
Browse Xerostomia studies →University Hospital, Basel, Switzerland is the lead sponsor of 989 studies on the registry; 189 are open to participants now.
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Exclusion Criteria:
healthy participants testing a candy in 5 different variations by (unstimulated and stimulated) salivary flow rate (before and after comparison)
Other: V01 candy · Other: V02 candy · Other: V03 candy · Other: V04 candy · Other: V05 candy
Other: V01 candy · Other: V02 candy · Other: V03 candy · Other: V04 candy · Other: V05 candy
Other: V01 candy · Other: V02 candy · Other: V03 candy · Other: V04 candy · Other: V05 candy
Other: V01 candy · Other: V02 candy · Other: V03 candy · Other: V04 candy · Other: V05 candy
Other: V01 candy · Other: V02 candy · Other: V03 candy · Other: V04 candy · Other: V05 candy
candy with sweetener (Isomalt) and apple flavour
candy with with sweetener (Isomalt) and apple flavour and acidifying agent (apple acid + citric acid)
candy with with sweetener (Isomalt) and apple flavour and acidifying agent (apple acid + citric acid) and Vitamin C
candy with sweetener (Isomalt) (control group 1)
candy with with sweetener (Isomalt) and acidifying agent (apple acid + citric acid) (control group 2)
dryness of mouth- sensation
dryness of mouth- sensation by Visual analogue scale (VAS); 0 = does not apply; 10 = is absolutely true.
Time frame: one point assessment following consumption of candy (approx 5 minutes)
Change in salivary flow rate (ml/min)
Change in salivary flow rate (ml/min) before and after stimulation (mechanical and gustatory) by consumption of candy
Time frame: before and after consumption of candy (approx 5 minutes for each salivary flow measurement)
This study is completed, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.
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University Hospital, Basel, Switzerland →