An observational study in Rheumatoid Arthritis, sponsored by Assiut University. Status unknown. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-09-16.
Sponsored by Assiut University · Observational
Rheumatoid arthritis (RA) is a common chronic systemic autoimmune disease that primarily affects the lining of the synovial joints which symmetrically involves the small joints, can cause cartilage and bone damage and associated with progressive disability, premature deaths, and socioeconomic burdens .
In RA, neuropathic pain "which is defined as pain caused by a lesion or a disease of the somatosensory system" , could be suggested by :nerve compression, associated comorbidities and vascuilitis .
Despite the recent advancement in RA treatment, neuropathic pain remains a cause of persistent pain even in controlled disease activity.
The prevalence of clinical neuropathy varies from 0.5% to 85% in patients with RA, which can cause functional disability . Foot and ankle pain is highly prevalent in RA with peripheral neuropathy is a common contributor to it . In previous studies , it was found that the most foot neuropathies are of tarsal tunnel syndrome, peroneal nerve entrapment and pure sensory axonal neuropathy.
For evaluation of neuropathic foot and ankle in RA , electrophysiological and imaging techniques can be very useful.
Nerve conduction study (NCS) is the electrodiagnostic evaluation of the function of peripheral nerves ,it can provide information regarding the presence, severity and location of a lesion, symmetricity of neuropathy, mononeuropathy or disorders affecting the neuromuscular junctions. Also, the functional modality most involved (sensory or motor) and the predominant pattern of pathology (e.g., axonal, demyelinating, or both.
Neuromascular ultrasond(NMUS) is a new modality of diagnosis developed in the past 20 years , and it can assess anatomical abnormalities that can't be evaluated by NCS NMUS being noninvasive and inexpensive diagnostic modality , it has been introduced as a complement to NCS for diagnosis of nerve conditions.
3,554 studies on the registry are indexed under Arthritis; 317 are open to participants now.
This study's planned enrollment of 80 is below the median of 155 across 1,057 observational studies indexed under Arthritis.
Browse Arthritis studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
RA patients with foot and ankle pain attending at both inpatient department and outpatient clinic
Exclusion Criteria:
neuromascular ultrasound of foot and ankle
Also known as: nerve conduction study
ultrasound parameters
nerve cross-section
Time frame: 3 years
nerve conduction parameters
nerve distal latency
Time frame: 3 years
painDETECT questionnaire
screening for neuropathic pain
Time frame: 1 year
No study locations are listed for this record.
This study is status unknown, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.
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Assiut University