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Status unknownNCT04458441w-piUpdated Mar 8, 2022

Can Warm Skin Disinfection Reduce the Pain Peripheral Central Catheter Application in Premature Babies?

An interventional study of warm group/cold group in Pain, Acute and Premature, sponsored by Zekai Tahir Burak Women's Health Research and Education Hospital. Status unknown at 1 site in Turkey. Open to participants aged Up to 1 Month. Per ClinicalTrials.gov, last updated 2022-03-08.

Sponsored by Zekai Tahir Burak Women's Health Research and Education Hospital · Not applicable, Interventional, and Supportive care

The sponsor has not verified this record recently (last verified Jul 2021), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
Up to 1 Month
Sex
All
01

Study summary

Peripheral central catheter application, especially in extremely low birth weight premature babies, is an intensive care follow-up procedure. There are many clinical studies in areas such as catheter type, skin disinfection, catheter duration, catheter infection. In our practice, it was observed that premature baby was less uncomfortable, the number of trials decreased, and the change in body temperature was less with the application of hot skin disinfection in our practice. With a prospective randomized study, the investigators wanted to document their observational data scientifically.

Read the detailed description

Babies under 32 gestation week and 1250 g who are treated at level 3 NICU and need peripheral central catheter will be included in the study. In the preparation of peripheral central catheter application, skin cleaning is performed with povidone iodine in our clinic. The investigators used during the povidione iodine preparation phase after heating the bain-marie method with sterile conditions. The investigators predicted that the premature baby would have less discomfort with warm povidion iodine. To demonstrate this, it was planned to take both video recordings during the application and N-PASS evaluation by an experienced person who does not know the povidone iodine temperature used .In preparation of the catheter except the person who did povidone iodine skin cleansing, nobody knows the heat. The catheters were administered by a single experienced person. The study was designed to be unaware of the povidin iodine application temperature of the person applying the catheter and the N-PASS assessment.

02

Conditions studied

  • Pain, Acute
  • Premature

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Keywords

  • premature, pain score, Picc line
03

Who can participate

Ages eligible
Up to 1 Month
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

Inclusion Criteria: below 32 gestational weeks and / or 1250 grams preterm babies neonates requiring total parenteral nutrition, antibiotic therapy for at least 7 days, -

Exclusion Criteria: major congenital anomalilies refusal to sign consent patient with previously attemped or placed central lines

-

04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Single group
Masking
Double (Care provider, Investigator)
Enrollment
30 participants (estimated)

Study arms

  • Active comparator
    warm skin desenfection group

    Povidion iodine will be used as a skin cleanser. povidion iodine will be heated sterile to 38 degrees with a ben-mari method and its temperature will be controlled by degrees. When it reaches the appropriate degree, the skin cleaning of the baby will be done sterile.

    Other: warm group/cold group

  • No intervention
    cold skin desenfection group

    Povidion iodine will be used as a skin cleanser. povidion iodine will be used in the skin cleaning of the baby without any heating procedure.

Interventions

  • Otherwarm group/cold group

    sequential randomization

05

What researchers measure

Primary outcomes

  1. change feeling of pain and restlessness in premature

    Evaluation of pain score in the patient during the procedure with n-pass evaluation

    Time frame: every 10 seconds before the 5 minutes and during the procedure

Secondary outcomes

  1. protection of body temperature

    body temperature monitoring before and during the incubator with skin temperature probe

    Time frame: before 5 min, during procedure

06

Study locations

1 of 1 sites recruiting
  • University of Health Sciences Istanbul Umraniye Teaching Hospital
    Istanbul, Turkey
    • funda atay · Contact
    Recruiting
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT04458441
Lead sponsor
Zekai Tahir Burak Women's Health Research and Education Hospital
Collaborators
Umraniye Education and Research Hospital
Responsible party
Funda Yavanoglu Atay (principal investigator, Zekai Tahir Burak Women's Health Research and Education Hospital) — Principal investigator
First posted
Jul 7, 2020
Start date
May 5, 2020
Primary completion
Sep 5, 2022 (estimated)
Completion
Dec 30, 2022 (estimated)
Last update
Mar 8, 2022

Study contacts

funda atay
Contact
funday.atay@gmail.com
+905054409167

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.

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