An interventional study of Hydrogen-rich water and Control Water in Aging, sponsored by University of Novi Sad, Faculty of Sport and Physical Education. Completed at 1 site in Serbia. Open to participants aged 70 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-04-27.
Sponsored by University of Novi Sad, Faculty of Sport and Physical Education · Not applicable, Interventional, and Prevention
This study evaluates the effects of six-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in men and women aged 70 years and over.
University of Novi Sad, Faculty of Sport and Physical Education is the lead sponsor of 19 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Hydrogen-rich water (Rejuvenation, HRW Natural Health Products Inc.) * 8 ppm of hydrogen * Administered one dose two times per day on an empty stomach in the morning and at the evening
Dietary Supplement: Hydrogen-rich water
Tap water * 0 ppm of hydrogen * Administered one dose two times per day on an empty stomach in the morning and at the evening
Other: Control Water
A tablet that produces hydrogen dissolved in a glass of water
A glass of tap water
Change in TeloTAGGG Telomerase PCR activity in serum
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in DNA methylation
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in blood concentration of advanced glycation end product
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in lipid peroxidation
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in serum FGF21
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in serum TET2
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in ADAS-Cog score (0-70 scale, higher scores indicating greater cognitive impairment)
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in facial wrinkling (0-100 scale; higher scores mean worse outcome)
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Change in maximal oxygen uptake estimated by step-in-place test
Baseline vs. 6 months
Time frame: Baseline vs. 6 months post-intervention
Plan to share: No
This study is completed, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.
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University of Novi Sad, Faculty of Sport and Physical Education