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Status unknownNCT04426058Updated Apr 20, 2022

CMP vs Fascia Iliaca Block

An interventional study of CMP and Fascia Illica in Pain, Postoperative and Hip Arthroplasty, sponsored by Loyola University. Status unknown at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-04-20.

Sponsored by Loyola University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Apr 2022), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Complete motorsparing protocol (CMP) has been developed to try to minimize the motor nerve block that is created when using Facia iliaca nerve block. The blocks performed in the (CMP) are the cluneal nerve block, Pericapsular nerve group block and lateral femoral cutaneous block. On the clinical trial, the investigators will randomize the participants that meet criteria to CMP or Fascia iliaca Block and compare the amount of opioid needed post op during 24 hours and their pain scores.

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Conditions studied

  • Pain, Postoperative
  • Hip Arthroplasty

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Keywords

  • Nerve Block
  • Fascia Iliaca Nerve Block
  • Complete Motor Sparing Protocol
  • Hip Arthroplasty
  • Pain control
03

In context

Pain, Postoperative

5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.

This study's planned enrollment of 40 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Loyola University is the lead sponsor of 132 studies on the registry; 15 are open to participants now.

Of its 26 completed or terminated interventional studies of FDA-regulated products, 23 (88%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Patients ≥ 18 years old
  • Patients undergoing total hip arthroplasty posterior approach.
  • Patients willing to participate and sign informed consent

Exclusion criteria

Exclusion Criteria:

  • Severe COPD/other contraindication to general anesthesia that spinal would be more suitable.
  • Patient with a weight of less than 41 kg
  • Dementia, not alert or Oriented to person, place, or time
  • Chronic pain patient with daily opioid use at home.
  • Patient with allergy to local anesthetics
  • Patient refusal
  • Total hip arthroplasty revision
  • Concomitant pain in different area from operative site.
  • Pregnancy
  • Patient with active infection on the injection sites for the blocks
  • Patients unable or willing to understand or comply with the study protocol
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    CMP

    Cluneal nerve Block 0.25% bupivacaine 20ml Pericapsular Nerve group block 0.25% Bupivacaine 20ml Lateral femoral cutaneous Block 0.25% bupivacaine 10ml

    Drug: CMP

  • Active comparator
    Fascia iliaca

    Fascia iliaca block suprainguinal technique 0.25% bupivacaine 50ml

    Drug: Fascia Illica

Interventions

  • DrugCMP

    Cluneal nerve Block 0.25% bupivacaine 20ml Pericapsular Nerve group block 0.25% Bupivacaine 20ml Lateral femoral cutaneous Block 0.25% bupivacaine 10ml

  • DrugFascia Illica

    Fascia iliaca block suprainguinal technique 0.25% bupivacaine 50ml

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What researchers measure

Primary outcomes

  1. Measurement of opioid use

    Measurement of opioid use (mg) for pain control after surgery once patient in recovery area

    Time frame: 24 hours

Secondary outcomes

  1. Measurement of the pain control

    Measurement of the pain control via numeric rating scale 0-10 where 0 is no pain and 10 is the worst pain.

    Time frame: 24 hours

07

Study locations

1 of 1 sites recruiting
  • Loyola University Medical Center
    Maywood, Illinois 60153, United States
    Recruiting
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References and documents

Publications

  • Tyagi A, Salhotra R. Total hip arthroplasty and peripheral nerve blocks: Limited but salient role? J Anaesthesiol Clin Pharmacol. 2018 Jul-Sep;34(3):379-380. doi: 10.4103/joacp.JOACP_114_18. No abstract available. PubMed 30386023 ↗
  • Adhikary SD, Short AJ, El-Boghdadly K, Abdelmalak MJ, Chin KJ. Transmuscular quadratus lumborum versus lumbar plexus block for total hip arthroplasty: A retrospective propensity score matched cohort study. J Anaesthesiol Clin Pharmacol. 2018 Jul-Sep;34(3):372-378. doi: 10.4103/joacp.JOACP_335_17. PubMed 30386022 ↗
  • Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847. PubMed 30063657 ↗
  • Hannon CP, Keating TC, Lange JK, Ricciardi BF, Waddell BS, Della Valle CJ. Anesthesia and Analgesia Practices in Total Joint Arthroplasty: A Survey of the American Association of Hip and Knee Surgeons Membership. J Arthroplasty. 2019 Dec;34(12):2872-2877.e2. doi: 10.1016/j.arth.2019.06.055. Epub 2019 Jul 8. PubMed 31371038 ↗
  • Kumar K, Pandey RK, Bhalla AP, Kashyap L, Garg R, Darlong V, Malhotra R, Yadav CS. Comparison of conventional infrainguinal versus modified proximal suprainguinal approach of Fascia Iliaca Compartment Block for postoperative analgesia in Total Hip Arthroplasty. A prospective randomized study. Acta Anaesthesiol Belg. 2015;66(3):95-100. PubMed 26767235 ↗

Study documents

  • Study protocol · Sep 18, 2020
  • Informed consent form · Dec 15, 2021

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 20, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04426058
Lead sponsor
Loyola University
Responsible party
Scott Byram MD (MD, Associate Professor, Loyola University) — Principal investigator
First posted
Jun 11, 2020
Start date
Jun 6, 2020
Primary completion
Dec 31, 2022 (estimated)
Completion
Dec 31, 2022 (estimated)
Last update
Apr 20, 2022

Study contacts

Carlos Martinez Parra, MD
Contact
carlos.martinezparra@lumc.edu
(708) 216-6462
Michael Majewski, MD
Contact
mimajewski@lumc.edu
(708) 216-6462

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.

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