An interventional study of two-sided approaches for iliac crest bone graft in Child and Osteotomy, sponsored by Yuxi Su. Completed at 1 site in China. Open to participants aged 2 Years to 16 Years. Per ClinicalTrials.gov, last updated 2020-06-11.
Sponsored by Yuxi Su · Not applicable, Interventional, and Treatment
The iliac crest is one of the most commonly used bone graft sources, especially in pediatric pelvic osteotomy operations for developmental dysplasia of the hip (DDH) and Legg-Calve-Perthes disease. In this study, we aimed to identify the effects of inner side and two-sided approaches for iliac crest bone harvesting on post-surgery ilium growth in children.
Autogenous bone grafting is still the gold standard and most effective method for treatment of non-union and bone defects due to congenital disease and infection. Despite the development of bone engineering, none of the allogeneic bone products can match the osteoinductive, osteoconductive, and immunogenic properties of autogenous bone. The iliac crest is one of the most harvested sites other than the fibula, ribs, and ulna. An iliac crest bone graft (ICBG) can supply a larger amount of cortical and cancellous bone than grafts from other donor sites. Pelvic osteotomy is widely used for treating developmental dysplasia of the hip (DDH) and Legg-Calve-Perthes disease. Tricortical structural bone such as that in the ilium is needed to stabilize the pelvis after osteotomy, and the anterior and posterior iliac crest are the two most used graft donor sites. When surgery is planned in the prone position, such as that for posterior spinal fusion, surgeons generally prefer to adopt the posterior approach for ICBG procedures. In supine position surgeries such as pelvic osteotomy for DDH or Legg-Calve-Perthes disease, surgeons prefer the anterior approach for ICBG procedures. There are many studies on iliac bone growth and complications after ICBG procedures. Most of the studies demonstrated good outcomes and few complications. However, according to our literature review, none of the previous studies used the iliac bone for transplantation in pelvic osteotomy. In this study, we compared the results between an inner table harvest site and an inner-outer table harvest site for ICBG used to maintain stability in pelvic osteotomy.
60 studies on the registry are indexed under Developmental Dysplasia of the Hip; 18 are open to participants now.
This study's enrollment of 47 is below the median of 59 across 38 interventional studies indexed under Developmental Dysplasia of the Hip.
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Exclusion Criteria:
An anterior approach was used to expose the inner table of the ilium.
both sides of the ilium were totally exposed of the ilium.
Procedure: two-sided approaches for iliac crest bone graft
Only one side of the ilium was exposed when surgery.
Radiographic parameters were evaluated on anteroposterior pelvic radiographs
The growth areas were measured by GE healthcare-Centricity RIS CE V3.0 software (General Electric Company). The areas was calculated as mm2.
Time frame: 3th month after surgery
Time for the totally recovery of iliac defect
the time was calculated from the surgery to the time totally recovery of iliac defect by days
Time frame: through study completion, an average of 6 months
Plan to share: No
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This study is completed, as verified in Jun 2020. You cannot join it, but the record below documents what was studied.
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Developmental Dysplasia of the Hip →
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