An observational study in Diabetes, Gestational and Pregnancy Diabetic, sponsored by Jena University Hospital. Status unknown at 1 site in Germany. Per ClinicalTrials.gov, last updated 2023-04-14.
Sponsored by Jena University Hospital · Observational
The primary objectives of the proposed project are to assess the long-term effects of prenatal exposure to gestational diabetes or diabetes on the maturation and health of the offspring. In addition, the long-term changes on the health of the affected mothers will be investigated, taking into account the metabolic adjustment during index pregnancy. The expected results will help to establish possible prevention strategies to fight the epidemic of non-communicable diseases for the offspring and the mothers.
Investigation of the long-term outcome of mother-child pairs after diabetic pregnancies and a comparison group regarding metabolic, cardiovascular, neurocognitive and reproductive long-term changes as a function of the course of pregnancy and metabolic control
842 studies on the registry are indexed under Diabetes, Gestational; 198 are open to participants now.
This study's planned enrollment of 100 is below the median of 200 across 269 observational studies indexed under Diabetes, Gestational.
Browse Diabetes, Gestational studies →Jena University Hospital is the lead sponsor of 62 studies on the registry; 19 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The study collective is composed of mother-child pairs after gestational diabetes, which were supervised in the Competence Center for Diabetes and Pregnancy at the University Hospital of Jena. The patients can decide to fill in an online questionnaire. For all other parts of the study, only patients who have been informed independently or on behalf of their legal guardian about the nature of the study after a detailed and understandable explanatory discussion with an investigator and who have given written consent will be included in the study.
Exclusion criteria:
The study collective is composed of mother-child pairs after gestational diabetes, which were supervised in the Competence Center for Diabetes and Pregnancy at the University Hospital of Jena. The patients can decide to fill in an online questionnaire. For all other parts of the study, only patients who have been informed individually or on behalf of their legal guardian about the nature of the study after a detailed and understandable explanatory discussion with an investigator and who have given written consent will be included in the study.
Other: Basic data collection (online survey or written form) · Other: Physical examination · Behavioral: Psychometric examination · Diagnostic Test: Recording of the adrenergic stress reaction (saliva test)
The control collective is composed of mother-child pairs who were cared for at the same time as the study collective at the University Hospital Jena. This collective is status post singleton pregnancy and term birth. The patients can decide to fill in an online questionnaire. For all other parts of the study, only patients who have been informed individually or on behalf of their legal guardian about the nature of the study after a detailed and understandable explanatory discussion with an investigator and who have given written consent will be included in the study.
Other: Basic data collection (online survey or written form) · Other: Physical examination · Behavioral: Psychometric examination · Diagnostic Test: Recording of the adrenergic stress reaction (saliva test)
Basic data collection is carried out by means of a questionnaire that participants can fill in outside the study centre. It contains questions about the current life situation, sleep and activity behaviour.
The physical examination takes place at the study centre and includes the measurement of height, current weight and body fat, as well as the recording of heart and circulation parameters (e.g. blood pressure measurement or determination of vascular health by means of ultrasound). General metabolic and hormonal parameters are analysed by means of a blood sample. In addition, a sugar test for diabetes diagnosis will be carried out.
Psychometric examination is carried out at the study centre with the help of a RIAS (Reynolds Intellectual Assessment Scales and Screening) test.
The adrenergic stress reaction is recorded by a saliva test.
Metabolic health
effects on metabolic health such as glucose tolerance disorders and diabetes mellitus, obesity and metabolic syndrome (mothers and children)
Time frame: 1 day examination at the study centre
Neurocognitive development
effects on neurocognitive development, mental health and adrenal and autonomic stress reactivity (mothers and children)
Time frame: 1 day examination at the study centre
Cardiovascular and vascular health
effects on cardiovascular and vascular health of blood pressure regulation and endothelial function (mothers and children)
Time frame: 1 day examination at the study centre
Maturation of the gonadal regulation
maturation of gonadal regulation, pubertal development and reproductive health (children)
Time frame: 1 day examination at the study centre
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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Jena University Hospital