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Active, not recruitingNCT04392908Updated Sep 26, 2025

Communication Memory of Cancer Diagnosis Within the Pediatric Triangle

An observational study in Memory, sponsored by Meyer Children's Hospital IRCCS. Active, not recruiting at 1 site in Italy. Open to participants aged 12 Years and older. Per ClinicalTrials.gov, last updated 2025-09-26.

Sponsored by Meyer Children's Hospital IRCCS · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
70
Ages
12 Years and older
Sex
All
01

Study summary

Present project aims to investigate memories related to a cancer communication diagnosis in pediatric oncology. It evaluates possible common elements and specificity between family and healthcare staff.

Read the detailed description

Lots of scientific evidences have shown that autobiographical episodes' narrative has a beneficial effect on the elaboration of memories. Indeed, narrating is a way to order thoughts and moods, which are connected to particular episodes of one's life, in order to rework and relive them. Since the diagnosis, a relationship and an open and sincere dialogue between the various parts of the pediatric triangle can promote a process of adaptation to the experience of illness and an integrated biopsychosocial healing. The first aim of this study is to explore and analyze autobiographical memories of pediatric patients, parents and healthcare staff. Also, it aims to investigate possible common and discordant element between deposition.

Phases of the present study:

  1. Sample recruitment and informed consent collection.
  2. Diagnosis communication audio recording.
  3. Communication of the autobiographical memory of the diagnosis audio recording of patients, parents, oncologist, nurse and psychologists involved, the day after the communication.
  4. Questionnaire APAM administration for adult participants.
  5. Audio Transcription and data coded. Data will be registered and operated by means of statistical software as SPSS (IBM) and T-Lab (Lancia, 2004).
  6. Statistical processing: ANOVA and t of Student tests will be implemented in order to compare collected questionnaires. Narrative analysis will be implemented by means of textual analysis software.
02

Conditions studied

  • Memory

Keywords

  • memory
  • pediatric cancer
  • oncology
  • communication
  • diagnosis
03

In context

Neoplasms

9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.

This study's planned enrollment of 70 is below the median of 204 across 1,683 observational studies indexed under Neoplasms.

Browse Neoplasms studies →

Lead sponsor

Meyer Children's Hospital IRCCS is the lead sponsor of 78 studies on the registry; 56 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
12 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients with cancer diagnosis; their parents and healthcare staff

Eligibility criteria

Inclusion criteria for pediatric patients:

  • age from 12 to 17 with cancer diagnosis only taken by Meyer Children's Hospital prior consent.
  • Italian speaking

Exclusion criteria for pediatric patients:

  • under 12 years old and above 17;
  • followed by other hospital;
  • cognitive disability

Inclusion criteria for parents:

- Italian speaking and signature informed consent.

Exclusion criteria for parents:

- cognitive disability

05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
70 participants (estimated)
Patient registry
No

Groups and cohorts

  • Patients

    Pediatric patients from 12 to 17 with cancer diagnosis only taken by Meyer Children's Hospital prior consent. Knowledge of fluent Italian language is required

    Other: Communication memory

  • Parents

    Parents of pediatric patients prior consent. Knowledge of fluent Italian language is required

    Other: Communication memory

  • Medical Staff

    Medical staff including doctor, psychologist and nurse

    Other: Communication memory

Interventions

  • OtherCommunication memory

    All groups will undergo audio-recorder interviews. Only adults will complete a self-report questionnaire on phenomenological aspects of autobiographical memories.

06

What researchers measure

Primary outcomes

  1. Phenomenological characteristics of autobiographical memory

    Self report questionnaire "Assessment of the Phenomenology of Autobiographical Memory - APAM"

    Time frame: One day after diagnosis

  2. Emotional characteristics of autobiographical memory

    linguistic analysis by Linguistic Inquiry Word Count - LIWC; cluster analysis by T-Lab; Content analysis; coherence and narrative structure by High Point Anaysis.

    Time frame: One day after diagnosis

07

Study locations

1 site
  • Meyer Children's Hospital
    Florence, Firenze 50139, Italy
08

References and documents

Publications

  • Bury M. Chronic illness as biographical disruption. Sociol Health Illn. 1982 Jul;4(2):167-82. doi: 10.1111/1467-9566.ep11339939. PubMed 10260456 ↗
  • Fioretti, C., & Smorti, A. (2015). How emotional content of memories changes in narrative. Narrative Inquire, 25(1), 37-56.
  • Fioretti C, Smorti A. Narrating positive versus negative memories of illness: does narrating influence the emotional tone of memories? Eur J Cancer Care (Engl). 2017 May;26(3). doi: 10.1111/ecc.12524. Epub 2016 Jun 8. PubMed 27271542 ↗
  • Giffard B, Viard A, Dayan J, Morel N, Joly F, Eustache F. Autobiographical memory, self, and stress-related psychiatric disorders: which implications in cancer patients? Neuropsychol Rev. 2013 Jun;23(2):157-68. doi: 10.1007/s11065-013-9233-6. Epub 2013 May 3. PubMed 23640242 ↗
  • Habermas T, Bluck S. Getting a life: the emergence of the life story in adolescence. Psychol Bull. 2000 Sep;126(5):748-69. doi: 10.1037/0033-2909.126.5.748. PubMed 10989622 ↗
  • Jankovic, M. & Puricelli, E. (2008). La comunicazione della diagnosi al bambino. In S. M. G. Adamo (A cura di), La cura della relazione in oncologia pediatrica. Milano: Raffaello Cortina.
  • Lancia, F. (2004). Strumenti per l'analisi dei testi: introduzione all'uso di T-Lab. Milano: Franco Angeli
  • Last BF, van Veldhuizen AM. Information about diagnosis and prognosis related to anxiety and depression in children with cancer aged 8-16 years. Eur J Cancer. 1996 Feb;32A(2):290-4. doi: 10.1016/0959-8049(95)00576-5. PubMed 8664044 ↗
  • Levi RB, Marsick R, Drotar D, Kodish ED. Diagnosis, disclosure, and informed consent: learning from parents of children with cancer. J Pediatr Hematol Oncol. 2000 Jan-Feb;22(1):3-12. doi: 10.1097/00043426-200001000-00002. PubMed 10695815 ↗
  • Malterud K, Siersma VD, Guassora AD. Sample Size in Qualitative Interview Studies: Guided by Information Power. Qual Health Res. 2016 Nov;26(13):1753-1760. doi: 10.1177/1049732315617444. Epub 2016 Jul 10. PubMed 26613970 ↗
  • McAdams, D. P. (2008). Personal narratives and the life story. In R. John, W. Robins & L. Pervin (Eds.), Handbook of personality: Theory and Research (3rd edn, pp. 241-261). New York: Guilford Press.
  • Nilsson-Ihrfelt E, Fjallskog ML, Liss A, Jakobsson O, Blomqvist C, Andersson G. Autobiographical memories in patients treated for breast cancer. J Psychosom Res. 2004 Oct;57(4):363-6. doi: 10.1016/j.jpsychores.2004.01.009. PubMed 15518671 ↗
  • Papini, M., Tringali, D., & Lauro-Grotto, R. (2011). La nostra era una vita normale. Ancona: Sorbello Editore.
  • Parker TM, Johnston DL. Parental perceptions of being told their child has cancer. Pediatr Blood Cancer. 2008 Oct;51(4):531-4. doi: 10.1002/pbc.21667. PubMed 18623217 ↗
  • Pennebaker, J., Fracis, M.E., & Booth, R.J. (2001). Linquistic Inquiry Word Count: LIWC 2001. Mahway: Lawrence Erlbaum Associates.
  • Smorti, A. (2007). Narrazioni. Cultura, memorie, formazione del sé. Firenze: Giunti.
  • Smorti, A. & Donzelli, G.P. (2015). La medicina narrativa in pediatria. Come le storie ci aiutano a capire la malattia. Firenze: SEID.
  • Sobo EJ. Good communication in pediatric cancer care: a culturally-informed research agenda. J Pediatr Oncol Nurs. 2004 May-Jun;21(3):150-4. doi: 10.1177/1043454204264408. PubMed 15296044 ↗
  • Tates K, Meeuwesen L. Doctor-parent-child communication. A (re)view of the literature. Soc Sci Med. 2001 Mar;52(6):839-51. doi: 10.1016/s0277-9536(00)00193-3. PubMed 11234859 ↗
  • Vannucci, M., Marchetti, I., Manili, A., Chiorri, C. (2010). "Come" ricordiamo il passato: Un nuovo strumento sulla fenomenologia della memoria autobiografica. Congresso Nazionale AIP; Sezione di Psicologia Sperimentale, Bologna, 2-4 Settembre 2010.
  • Vannucci M, Chiorri C, Marchetti I. Shaping our personal past: Assessing the phenomenology of autobiographical memory and its association with object and spatial imagery. Scand J Psychol. 2020 Oct;61(5):599-606. doi: 10.1111/sjop.12639. Epub 2020 Apr 4. PubMed 32246729 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 26, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04392908
Lead sponsor
Meyer Children's Hospital IRCCS
Collaborators
University of Florence
Responsible party
Rosanna Martin (Principal Investigator, Meyer Children's Hospital IRCCS) — Principal investigator
First posted
May 19, 2020
Start date
Sep 1, 2019
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Sep 26, 2025

Study contacts

Chiara Fioretti, PhD
study chair · Laboratorio di Metodi e Tecniche di Analisi delle Esperienze di Malattia Dipartimento di Scienze della Formazione e Psicologia, Università degli Studi di Firenze

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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