An interventional study of Medium Chain Triglyceride oil in Pharmacokinetics, sponsored by University of Alberta. Completed at 1 site in Canada. Open to participants aged 21 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-05-15.
Sponsored by University of Alberta · Not applicable, Interventional, and Health services research
Assessing Ketone levels achieved after varying doses of Medium Chain Triglyceride (MCT) oil
Assessing Ketone levels achieved after varying doses of Medium Chain Triglyceride (MCT) oil in three study populations: \<65 year healthy, 65 and older healthy, and Alzheimer's disease.
Each subject attends for 4 study days, receiving incrementally larger MCT doses at each visit for 0g, to 14g, to 28g to 42g.
University of Alberta is the lead sponsor of 800 studies on the registry; 168 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Four study days. Day 1 administered 0g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 2 administered 14g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 3 administered 28g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 4 administered 42g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter (All MCT doses administered as a single dose at time 0)
Dietary Supplement: Medium Chain Triglyceride oil
Four study days. Day 1 administered 0g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 2 administered 14g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 3 administered 28g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 4 administered 42g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter. (All MCT doses administered as a single dose at time 0)
Dietary Supplement: Medium Chain Triglyceride oil
Four study days. Day 1 administered 0g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 2 administered 14g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 3 administered 28g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter Day 4 administered 42g MCT oil with baseline and hourly betahydroxybutyrate (BHB) measures (by fingerstick test) for 5 hours thereafter. (All MCT doses administered as a single dose at time 0)
Dietary Supplement: Medium Chain Triglyceride oil
Bulletproof Braine Octane MCT oil
Maximum plasma concentration (Cmax)
Calculation of Cmax to varying doses in each subject and in different study arms.
Time frame: 3 months
Time to maximum plasma concentration (tmax)
Calculation of tmax to varying doses in each subject and in different study arms.
Time frame: 3 months
Area under the curve (AUC)
Calculation of AUC to varying doses in each subject and in different study arms.
Time frame: 3 months
weight
measured in kg
Time frame: 3months
height
measured in cm
Time frame: 3 months
BMI
Calculated BMI (ht/m2)
Time frame: 3months
Body fat
% measured by bioimpedence scale
Time frame: 3 months
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in May 2020. You cannot join it, but the record below documents what was studied.
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