An observational study in Iodine Deficiency, sponsored by Swiss Federal Institute of Technology. Completed at 10 sites in 10 countries. Open to participants aged 6 Years to 12 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-01-25.
Sponsored by Swiss Federal Institute of Technology · Observational
Many of the Caribbean island nations have no data on iodine status in their populations.
Iodine deficiency in children can reduce IQ but can be easily corrected through a program of salt iodization.
The study will be located at 11 islands of the Caribbean region. At each of the 11 study sites, we will measure the iodine status in school-age children by collecting morning spot urine samples for measurement of urinary iodine concentration (UIC). We will also measure height and weight in all children. We will collect a repeat, next-day spot urine sample in 1/3rd of children to adjust for intra-individual variation in spot UIC and calculate the distribution of population intake.
In well-controlled randomized trials in Europe and New Zealand, even mild-to-moderate iodine deficiency in school-age children reduces IQ (1); thus, its critical to avoid iodine deficiency in this age group. In countries effected by iodine deficiency, its sustainable elimination through iodized salt can contribute to socioeconomic development. The goal to eliminate iodine deficiency was first adopted globally at the World Summit for Children in 1990, and in 1994, WHO and UNICEF concluded that salt iodization is a safe, cost-effective and sustainable strategy to control iodine deficiency (2). In 2005, the World Health Assembly called on national governments to report on their iodine nutrition every three years. However, before the present survey, the ten countries included in this project had no data on iodine status in their populations, and household access to adequately iodized salt was also unknown. Thus, the study objectives were:
Swiss Federal Institute of Technology is the lead sponsor of 154 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Children of school age
Inclusion Criteria:
School aged children 6 - 12 years living in Jamaica
School aged children 6 - 12 years living in Trinidad and Tobago
School aged children 6 - 12 years living in Belize
School aged children 6 - 12 years living in Barbados
School aged children 6 - 12 years living in St. Lucia
School aged children 6 - 12 years living in Grenada
School aged children 6 - 12 years living in St. Vincent \& the Grenadines
School aged children 6 - 12 years living in Antigua
School aged children 6 - 12 years living in Dominica
School aged children 6 - 12 years living in St. Kitts and Nevis
Iodine status (UIC in spot urine samples)
Assessment of iodine status based on median urinary iodine concentration in spot urine samples
Time frame: March 2018 to May 2019
Iodine content in salt
Measurement of iodine concentration in salt samples brought in by participants
Time frame: January 2019 to May 2019
Ran from Jan 2018 to primary completion in May 2018, 4 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
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