An interventional study of Human biological samples in Coronavirus Infections, Severe Acute Respiratory Syndrome and SARS-CoV Infection, sponsored by Institut Pasteur. Completed at 4 sites in 3 countries. Per ClinicalTrials.gov, last updated 2022-02-15.
Sponsored by Institut Pasteur · Not applicable, Interventional, and Screening
This study is a interventional study that present minimal risks and constraints to evaluate the presence of novel coronavirus (SARS-CoV-2) or antibodies among individuals living in households where there is a confirmed coronavirus case in order to provide useful information on the proportion of symptomatic forms and the extent of the virus transmission in tropical regions such as French Guiana, Guadeloupe and New-Caledonia.
This study is a interventional study that present minimal risks and constraints to evaluate the presence of novel coronavirus (SARS-CoV-2) or antibodies among individuals living in households where there is a confirmed coronavirus case in order to provide useful information on the proportion of symptomatic forms and the extent of the virus transmission in tropical regions such as French Guiana, Guadeloupe and New-Caledonia.
Subjects will be assessed (questionnaires and sampling) in their homes. Subjects will be asked to attend study visits at days 0, 7, 14, 21, 28, 60, 90, 180 and 360.
The primary objective of the study is to evaluate the rate of intra-household secondary transmission of the virus.
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's enrollment of 245 is above the median of 120 across 4,201 interventional studies indexed under Infections.
Browse Infections studies →Institut Pasteur is the lead sponsor of 96 studies on the registry; 40 are open to participants now.
Counted across the registry records on this site, refreshed daily.
or Family contact in French Guiana and Guadeloupe: person who lived in the same household as the primary case of COVID-19 when the primary case was symptomatic. A household is defined as a group of people (2 or more) living in the same accommodation (excluding residential institutions such as boarding schools, dormitories, hostels, prisons, other communities hosting grouped people),
or Close contact in New-Caledonia: any individual who was in contact with a primary case, in his/her family/living environment, work/school, friends/leisure or means of transport, when the primary case was symptomatic or presymptomatic,
Exclusion Criteria:
Subject with laboratory-confirmed coronavirus SARS-CoV-2 infection by polymerase chain reaction (PCR)
Procedure: Human biological samples
Subject who lived in the household of the primary case while the primary case was symptomatic
Procedure: Human biological samples
* Blood sample * Nasopharyngeal swab.
Evaluation of the extent of the virus transmission within households
The extent of the virus transmission within households will be assessed by evaluating the rate of intra-household secondary transmission of the virus
Time frame: 2 years
Characterization of the secondary cases
The characterization of the secondary cases will be assessed by evaluating the proportion of asymptomatic forms within the household
Time frame: 2 years
Characterization of the secondary cases
The characterization of the secondary cases will be assessed by characterizing the risk factors for coronavirus infection.
Time frame: 2 years
In New-Caledonia, evaluation of the extent of the virus transmission within contact persons
The extent of the virus transmission within contact persons will be assessed by evaluating the rate of extended-contact secondary transmission of the virus
Time frame: 2 years
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2022. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Institut Pasteur