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Active, not recruitingNCT04324008Updated Dec 3, 2025

Clinical Comparison of Different Flowable Resin Composites

An interventional study of Constic and G-ænial Universal Flo in Tooth Diseases, sponsored by Hacettepe University. Active, not recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-03.

Sponsored by Hacettepe University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 2 years 4 months after the study started (first participant enrolled Nov 2017, registered Mar 2020).
Phase
Not applicable
Study type
Interventional
Enrollment
28
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The aim of this study is to evaluate a self-adhesive flowable resin composite, a flowable resin composite with high viscosity and a conventional flowable resin composite in combination with a universal adhesive using two different application modes. All patients will receive at least 4 occlusal restorations. Cavities will be divided into four groups according to restorative systems used: Constic (a self-adhering flowable composite), G-ænial Universal Flo (a highly filled flowable composite), Tetric N-Flow (self-etch) (a conventional flowable composite), Tetrin N-Flow (etch\&rinse).

02

Conditions studied

  • Tooth Diseases

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Keywords

  • flowable resin composite
  • occlusal
03

In context

Tooth Diseases

79 studies on the registry are indexed under Tooth Diseases; 11 are open to participants now.

This study's enrollment of 28 is below the median of 49 across 63 interventional studies indexed under Tooth Diseases.

Browse Tooth Diseases studies →

Lead sponsor

Hacettepe University is the lead sponsor of 1,007 studies on the registry; 214 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • having no medical or behavioral problems preventing then from attending review visits
  • absence of previously placed restorations
  • having antagonist teeth

Exclusion criteria

Exclusion Criteria:

  • poor gingival health
  • uncontrolled, rampant caries
  • bruxism
  • removable partial dentures
  • xerostomia
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
28 participants (actual)

Study arms

  • Experimental
    Constic

    Constic (DMG, Hamburg, Germany)

    Device: Constic

  • Experimental
    G-ænial Universal Flo

    G-ænial Universal Flo (GC Corporation, Tokyo, Japan) in combination with G-Premio Bond (self-etch mode)

    Device: G-ænial Universal Flo

  • Experimental
    Tetric N-Flow (self-etch)

    Tetric N-Flow (Ivoclar Vivadent, Schaan, Liechtenstein) in combination with Tetric N-Bond Universal (self-etch mode)

    Device: Tetric N-Flow (self-etch)

  • Experimental
    Tetric N-Flow (etch&rinse)

    Tetric N-Flow (Ivoclar Vivadent, Schaan, Liechtenstein) in combination with Tetric N-Bond Universal (etch\&rinse mode)

    Device: Tetric N-Flow (etch&rinse)

Interventions

  • DeviceConstic

    Flowable resin composite

  • DeviceG-ænial Universal Flo

    Flowable resin composite

  • DeviceTetric N-Flow (self-etch)

    Tetric N-Flow (Tetric N-Bond Universal, self-etch mode)

  • DeviceTetric N-Flow (etch&rinse)

    Tetric N-Flow (Tetric N-Bond Universal, etch\&rinse mode)

06

What researchers measure

Primary outcomes

  1. Clinical performances of different flowable resin composite

    Two year results according to USPHS criteria

    Time frame: two years

07

Study locations

1 site
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 3, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT04324008
Responsible party
Dr. Fatma Dilşad Öz (Assistant Professor, Hacettepe University) — Principal investigator
First posted
Mar 27, 2020
Start date
Nov 1, 2017
Primary completion
Jan 1, 2018
Completion
Nov 1, 2026 (estimated)
Last update
Dec 3, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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